Evidence map›Paper›PMID 38004956›Full record

ArticleMicromachines2023

Design, Simulation and Multi-Objective Optimization of a Micro-Scale Gearbox for a Novel Rotary Peristaltic Pump.

Nikolaos Rogkas, Matthaios Pelekis, Alexandros Manios, Alexandros Anastasiadis, Georgios Vasileiou, Achilleas Tsoukalis, Christos Manopoulos, Vasilios Spitas

Abstract read
In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nikolaos RogkasLaboratory of Machine Design and Dynamics, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.ORCID 0000-0002-4581-5639
Matthaios PelekisLaboratory of Machine Design and Dynamics, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.ORCID 0009-0009-0692-3002
Alexandros ManiosLaboratory of Machine Design and Dynamics, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.ORCID 0009-0006-7659-1742
Alexandros AnastasiadisLaboratory of Machine Design and Dynamics, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.ORCID 0000-0003-4677-9550
Georgios VasileiouLaboratory of Machine Design and Dynamics, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.ORCID 0000-0003-3496-0619
Achilleas TsoukalisMicrel Medical Devices SA, Koropi, 19441 Athens, Greece.
Christos ManopoulosBiofluid Mechanics & Biomedical Technology Laboratory, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.ORCID 0000-0002-3560-4221
Vasilios SpitasLaboratory of Machine Design and Dynamics, School of Mechanical Engineering, National Technical University of Athens, Zografos, 15780 Athens, Greece.

Funding

This research was funded by the European Union and Greek national funds through the Opera-tional Program Competitiveness, Entrepreneurship and Innovation, under the call RE-SEARCH-CREATE-INNOVATE project code: T1EDK-01366, MIS: 5032787
6 · The paper itself

Abstract

Peristaltic pumps are widely used in biomedical applications to ensure the safe flow of sterile or medical fluids. They are commonly employed for drug injections, IV fluids, and blood separation (apheresis). These pumps operate through a progressive contraction or expansion along a flexible tube, enabling fluid flow. They are also utilized in industrial applications for sanitary fluid transport, corrosive fluid handling, and novel pharmacological delivery systems. This research provides valuable insights into the selection and optimal design of the powertrain stages for peristaltic pumps implemented in drug delivery systems. The focus of this paper lies in the simulation and optimization of the performance of a power transmission gearbox by examining the energy consumption, sound levels, reliability, and volume as output metrics. The components of the powertrain consist of a helical gear pair for the first stage, a bevel gear pair for the second one, and finally a planetary transmission. Through extensive simulations, the model exhibits promising results, achieving an efficiency of up to 90%. Furthermore, alternative configurations were investigated to optimize the overall performance of the powertrain. This process has been simulated by employing the KISSsoft/KISSsys software package. The findings of this investigation contribute to advancements in the field of biomedical engineering and hold significant potential for improving the efficiency, reliability, and performance of drug delivery mechanisms.

Indexed as

drug delivery systemsgearboxoptimizationperistaltic pump

Identifiers

PMID38004956
PMCPMC10673108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.