Evidence map›Paper›PMID 38004809›Full record

ArticleMicroorganisms2023

SARS-CoV-2 Papain-like Protease Negatively Regulates the NLRP3 Inflammasome Pathway and Pyroptosis by Reducing the Oligomerization and Ubiquitination of ASC.

Huan Meng, Jianglin Zhou, Mingyu Wang, Mei Zheng, Yaling Xing, Yajie Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Volatile oil ofFrontiers in pharmacology · 2025
    Review
  5. Saponin components inFrontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Huan MengDepartment of Clinical Laboratory, Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing 100015, China.ORCID 0000-0002-7577-6626
Jianglin ZhouBioinformatics Center of Academy of Military Medicine Science, Beijing 100850, China.ORCID 0000-0002-6598-7390
Mingyu WangBioinformatics Center of Academy of Military Medicine Science, Beijing 100850, China.
Mei ZhengDepartment of Clinical Laboratory, Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing 100015, China.
Yaling XingBioinformatics Center of Academy of Military Medicine Science, Beijing 100850, China.
Yajie WangDepartment of Clinical Laboratory, Beijing Ditan Hospital, Capital Medical University, Chaoyang District, Beijing 100015, China.
Academy of Military Medical Sciences · CNCapital Medical University · CN

Funding

National Natural Science Foundation of China 82072285
6 · The paper itself

Abstract

The interaction of viruses with hosts is complex, especially so with the antiviral immune systems of hosts, and the underlying mechanisms remain perplexing. Infection with

Indexed as

ASCdeubiquitinationIL-1βNLRP3 inflammasomepapain-like proteasepyroptosisSARS-CoV-2

Identifiers

PMID38004809
PMCPMC10673202
OpenAlexW4388760427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.