Evidence map›Paper›PMID 38004770›Full record

ReviewMicroorganisms2023

Molecular Diagnosis as an Alternative for Public Health Surveillance of Leptospirosis in Colombia.

Margarita Arboleda, Mariana Mejía-Torres, Maritza Posada, Nicaela Restrepo, Paola Ríos-Tapias, Luis Alberto Rivera-Pedroza, David Calle, Miryan M Sánchez-Jiménez, Katerine Marín, Piedad Agudelo-Flórez

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Molecular Characterization ofTropical medicine and infectious disease · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Margarita ArboledaTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Mariana Mejía-TorresTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.ORCID 0009-0001-7831-9930
Maritza PosadaTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Nicaela RestrepoTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Paola Ríos-TapiasTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Luis Alberto Rivera-PedrozaTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
David CalleTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Miryan M Sánchez-JiménezTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Katerine MarínTropical Medicine Group, Colombian Institute of Tropical Medicine, Sabaneta 055450, Colombia.
Piedad Agudelo-FlórezGraduate School, Universidad CES, Medellín 050021, Colombia.ORCID 0000-0002-0002-776X
Instituto Colombiano de Medicina Tropical · COClínica CES · CO

Funding

Research Training Program on the Impact of Zoonotic and Vector-borne Viruses, Rickettsiae, and Leptospira in Acute Undifferentiated Febrile IllnessesD43TW010331 · FIC · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AGUILAR, PATRICIA VERONICA, RODAS, JUAN DAVID · 2016 to 2025
$2.6M
FIC NIH HHS D43 TW010331
6 · The paper itself

Abstract

Leptospirosis represents a public health problem in Colombia. However, the underreporting of the disease is an unfortunate reality, with a clear trend towards a decrease in cases since 2019, when the guidelines for its confirmatory diagnosis changed with the requirement of two paired samples. The purpose of this review is to highlight the importance of leptospirosis. While the access to rapid diagnosis is available at practically all levels of care for dengue and malaria, leptospirosis-a doubly neglected disease-deserves recognition as a serious public health problem in Colombia. In this manner, it is proposed that molecular tests are a viable diagnostic alternative that can improve the targeted treatment of the patient and the timeliness of data and case reporting to SIVIGILA, and reduce the underreporting of the disease. Taking advantage of the strengthened technological infrastructure derived from the SARS-CoV-2 pandemic for molecular diagnosis in Colombia, with a network of 227 laboratories distributed throughout the national territory, with an installed capacity for PCR testing, it is proposed that molecular diagnosis can be used as an alternative for early diagnosis. This would allow case confirmation through the public health network in Colombia, and, together with the microagglutination (MAT) technique, the epidemiological surveillance of this disease in this country would be strengthened.

Indexed as

ColombiadiagnosisleptospirosisPCRpublic health surveillance

Identifiers

PMID38004770
PMCPMC10673046
OpenAlexW4388639119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.