Evidence map›Paper›PMID 38004633›Full record

ArticleMicroorganisms2023

Endoscopic Diagnosis and Therapy for Epstein-Barr Virus-Associated Gastric Cancer.

Hideo Yanai, Junko Fujiwara, Eiichiro Toyama, Hiroshi Okuda, Osamu Miura, Seiji Kaino, Jun Nishikawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hideo YanaiDepartment of Clinical Research, Hofu Institute of Gastroenterology, 14-33 Ekiminami, Hofu 747-0801, Yamaguchi, Japan.
Junko FujiwaraDepartment of Gastroenterology & Hepatology, Hofu Institute of Gastroenterology, 14-33 Ekiminami, Hofu 747-0801, Yamaguchi, Japan.
Eiichiro ToyamaDepartment of Surgery, Hofu Institute of Gastroenterology, 14-33 Ekiminami, Hofu 747-0801, Yamaguchi, Japan.
Hiroshi OkudaDepartment of Surgery, Hofu Institute of Gastroenterology, 14-33 Ekiminami, Hofu 747-0801, Yamaguchi, Japan.
Osamu MiuraDepartment of Surgery, Hofu Institute of Gastroenterology, 14-33 Ekiminami, Hofu 747-0801, Yamaguchi, Japan.
Seiji KainoDepartment of Clinical Research, National Hospital Organization Kanmon Medical Center, 1-1 Sotoura, Chofu, Shimonoseki 752-8510, Yamaguchi, Japan.
Jun NishikawaDepartment of Laboratory Science, Yamaguchi University Graduate School of Medicine, 1-1-1Minamikogushi, Ube 755-8505, Yamaguchi, Japan.ORCID 0000-0002-6695-9754
National Hospital Organization · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr-virus-associated gastric cancer (EBVaGC) represents almost 7% of all GC and is a distinct subtype of GC with extreme DNA hypermethylation. EBVaGC is a tumor-infiltrating lymphocyte-rich tumor with little lymph-node metastasis in its early stage and with a relatively favorable prognosis in its advanced stage. Using upper gastrointestinal endoscopy, we recognize EBVaGC as a mainly depressed type with SMT-like protrusion in the upper part of the stomach near the gastric mucosal atrophic border or remnant stomach. The EBVaGC recognition rate of 21.4% with the endoscopic motif is not high, and further progress in endoscopic diagnosis of EBVaGC is needed. As less invasive endoscopic therapy, the extension of the criteria of endoscopic submucosal dissection (ESD) for early EBVaGC with little lymph-node metastasis should be discussed. Endoscopic diagnosis of EBVaGC may be relevant for the selection of patients who could benefit from endoscopic treatment or chemotherapy.

Indexed as

carcinoma with lymphoid stroma (CLS)endoscopic diagnosisendoscopic submucosal dissection (ESD)endoscopic therapyEpstein–Barr-virus-associated gastric cancerEpstein–Barr virus (EBV)Helicobacter pylori

Identifiers

PMID38004633
PMCPMC10673609
OpenAlexW4387907454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.