Evidence map›Paper›PMID 38004595›Full record

ReviewPharmaceutics2023

Photodynamic Therapy-Induced Anti-Tumor Immunity: Influence Factors and Synergistic Enhancement Strategies.

Wenxin Chou, Tianzhen Sun, Nian Peng, Zixuan Wang, Defu Chen, Haixia Qiu, Hongyou Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. MnOPharmaceutics · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. The Latest Look at PDT and Immune Checkpoints.Current issues in molecular biology · 2024
    Review
  20. Advances in Nanodynamic Therapy for Cancer Treatment.Nanomaterials (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wenxin ChouSchool of Medical Technology, Beijing Institute of Technology, Beijing 100081, China.
Tianzhen SunSchool of Medical Technology, Beijing Institute of Technology, Beijing 100081, China.ORCID 0009-0000-7718-3667
Nian PengSchool of Medical Technology, Beijing Institute of Technology, Beijing 100081, China.
Zixuan WangDepartment of Laser Medicine, the First Medical Center, PLA General Hospital, Beijing 100853, China.
Defu ChenSchool of Medical Technology, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0002-7198-1104
Haixia QiuDepartment of Laser Medicine, the First Medical Center, PLA General Hospital, Beijing 100853, China.ORCID 0000-0002-6556-4523
Hongyou ZhaoSchool of Medical Technology, Beijing Institute of Technology, Beijing 100081, China.ORCID 0000-0003-4564-3176
Beijing Institute of Technology · CNChinese PLA General Hospital · CN

Funding

CAMS Innovation Fund for Medical Sciences (CIFMS) 2019-I2M-5-061the Beijing Institute of Technology Research Fund Program for Young Scholars XSQD-202023003the Major Program of the National Natural Science Foundation of China T2293750the Major Program of the National Natural Science Foundation of China T2293753the National Key R&D Program of China 2022YFA1207600
6 · The paper itself

Abstract

Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity towards tumor cells by activating photosensitizers (PSs) with light exposure to produce reactive oxygen species (ROS). Compared to traditional treatment strategies such as surgery, chemotherapy, and radiation therapy, PDT not only kills the primary tumors, but also effectively suppresses metastatic tumors by activating the immune response. However, the anti-tumor immune effects induced by PDT are influenced by several factors, including the localization of PSs in cells, PSs concentration, fluence rate of light, oxygen concentration, and the integrity of immune function. In this review, we systematically summarize the influence factors of anti-tumor immune effects mediated by PDT. Furthermore, an update on the combination of PDT and other immunotherapy strategies are provided. Finally, the future directions and challenges of anti-tumor immunity induced by PDT are discussed.

Indexed as

combination therapyinfluence factorsinnate immunityphotodynamic therapyspecific immunity

Identifiers

PMID38004595
PMCPMC10675361
OpenAlexW4388635684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.