Evidence map›Paper›PMID 38004594›Full record

ArticlePharmaceutics2023

Comparison of Sonodynamic Treatment Set-Ups for Cancer Cells with Organic Sonosensitizers and Nanosonosensitizers.

Aleksandar Radivoievych, Svitlana Prylutska, Oliver Zolk, Uwe Ritter, Marcus Frohme, Anna Grebinyk

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Aleksandar RadivoievychDivision Molecular Biotechnology and Functional Genomics, Technical University of Applied Sciences Wildau, Hochschulring 1, 15745 Wildau, Germany.
Svitlana PrylutskaDepartment of Plants Physiology, Biochemistry and Bioenergetics, National University of Life and Environmental Science of Ukraine, Heroyiv Oborony Str., 15, 03041 Kyiv, Ukraine.
Oliver ZolkFaculty of Health Sciences, Joint Faculty of the Brandenburg University of Technology Cottbus-Senftenberg, The Brandenburg Medical School Theodor Fontane and the University of Potsdam, 14476 Potsdam, Germany.
Uwe RitterInstitute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693 Ilmenau, Germany.ORCID 0000-0002-9315-4863
Marcus FrohmeDivision Molecular Biotechnology and Functional Genomics, Technical University of Applied Sciences Wildau, Hochschulring 1, 15745 Wildau, Germany.ORCID 0000-0001-9063-2682
Anna GrebinykDivision Molecular Biotechnology and Functional Genomics, Technical University of Applied Sciences Wildau, Hochschulring 1, 15745 Wildau, Germany.ORCID 0000-0002-4651-7908
University of Potsdam · DEDeutsches Elektronen-Synchrotron DESY · DENational University of Life and Environmental Sciences of Ukraine · UATechnical University of Applied Sciences Wildau · DETechnische Universität Ilmenau · DE

Funding

German Academic Exchange Service 91775672Strengthening technological and application-oriented research at scientific institutions (StaF Directive) 85037298
6 · The paper itself

Abstract

Cancer sonodynamic therapy (SDT) is the therapeutic strategy of a high-frequency ultrasound (US) combined with a special sonosensitizer that becomes cytotoxic upon US exposure. The growing number of newly discovered sonosensitizers and custom US in vitro treatment solutions push the SDT field into a need for systemic studies and reproducible in vitro experimental set-ups. In the current research, we aimed to compare two of the most used and suitable SDT in vitro set-ups-"sealed well" and "transducer in well"-in one systematic study. We assessed US pressure, intensity, and temperature distribution in wells under US irradiation. Treatment efficacy was evaluated for both set-ups towards cancer cell lines of different origins, treated with two promising sonosensitizer candidates-carbon nanoparticle C

Indexed as

apoptosisberberineC60 fullerenesonodynamic therapyultrasound

Identifiers

PMID38004594
PMCPMC10674572
OpenAlexW4388635247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.