Evidence map›Paper›PMID 38004553›Full record

ReviewPharmaceutics2023

Exploiting Benefits of Vaterite Metastability to Design Degradable Systems for Biomedical Applications.

Yulia Svenskaya, Tatiana Pallaeva

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Systematic Study of Preparing Porous CaCONanomaterials (Basel, Switzerland) · 2025
    Article
  4. Beyond carbonate biomineralization: why prokaryote-driven COFrontiers in bioengineering and biotechnology · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yulia SvenskayaScientific Medical Center, Saratov State University, 410012 Saratov, Russia.ORCID 0000-0002-6359-2969
Tatiana PallaevaFSRC "Crystallography and Photonics" RAS, 119333 Moscow, Russia.ORCID 0000-0003-4076-5078

Funding

Russian Ministry of Education and Science within the State assignment FSRC «Crystallography and Photonics» RASRussian Science Foundation 22-73-10194
6 · The paper itself

Abstract

The widespread application of calcium carbonate is determined by its high availability in nature and simplicity of synthesis in laboratory conditions. Moreover, calcium carbonate possesses highly attractive physicochemical properties that make it suitable for a wide range of biomedical applications. This review provides a conclusive analysis of the results on using the tunable vaterite metastability in the development of biodegradable drug delivery systems and therapeutic vehicles with a controlled and sustained release of the incorporated cargo. This manuscript highlights the nuances of vaterite recrystallization to non-porous calcite, dissolution at acidic pH, biodegradation at in vivo conditions and control over these processes. This review outlines the main benefits of vaterite instability for the controlled liberation of the encapsulated molecules for the development of biodegradable natural and synthetic polymeric materials for biomedical purposes.

Indexed as

anticancer therapyantimicrobial therapyayer-by-layer assemblybiodegradationbufferingCaCO3 particlescalcitecalcium carbonatecalcium ionscarbon dioxide bubblescavitationcontrolled releasedegradationdissolutionmetastabilityossificationpH-sensitivityrecrystallizationresorptiontheranosticsUS imagingvaterite

Identifiers

PMID38004553
PMCPMC10674703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.