OMNI: Gas Chromatograph Captures Seven Common PET Radiotracer Analytes in under 5 Minutes.

Camry Vonyae' A'Keen, Jakub Mroz, Simon Kunta Joseph, Jairo Baquero, Melchor V Cantorias, Patrick Carberry

Abstract read

In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camry Vonyae' A'KeenDepartment of Radiology, New York University Grossman School of Medicine, 660 First Avenue, Room 240, New York, NY 10016, USA.

Jakub MrozDepartment of Radiology, New York University Grossman School of Medicine, 660 First Avenue, Room 240, New York, NY 10016, USA.

Simon Kunta JosephDepartment of Radiology, New York University Grossman School of Medicine, 660 First Avenue, Room 240, New York, NY 10016, USA.

Jairo BaqueroDepartment of Radiology, New York University Grossman School of Medicine, 660 First Avenue, Room 240, New York, NY 10016, USA.

Melchor V CantoriasDepartment of Radiology, New York University Grossman School of Medicine, 660 First Avenue, Room 240, New York, NY 10016, USA.

Patrick CarberryDepartment of Radiology, New York University Grossman School of Medicine, 660 First Avenue, Room 240, New York, NY 10016, USA.ORCID 0000-0001-7702-4674

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel gas chromatography method was developed using automatic injections to identify and quantify the amount of residual solvents or analytes in samples of fluorine-18 and carbon-11 radiopharmaceuticals. This approach evaluates seven analytes in less than 5 versus 13 min of acquisition time. The method additionally includes a 3 min bakeout to aid in the removal and carry-over of higher-boiling impurities. Chromatographic parameters such as column temperature, hold time, column pressure, flow rate, and split ratios were adjusted and optimized to analyze radioactive drug samples containing analytes which include methanol, ethanol, acetone, acetonitrile, triethylamine,

Indexed as

analytescarbon-11fluorine-18gas chromatographypositron emission tomographyquality controlradiotracer

Identifiers

PMID38004488

DOI10.3390/ph16111623

PMCPMC10675356

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.