Evidence map›Paper›PMID 38004486›Full record

ReviewPharmaceuticals (Basel, Switzerland)2023

Theranostic Imaging Surrogates for Targeted Alpha Therapy: Progress in Production, Purification, and Applications.

Bryce J B Nelson, John Wilson, Jan D Andersson, Frank Wuest

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. [International journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Single Photon Emission Computed Tomography Tracer.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. EJNMMI radiopharmacy and chemistry · 2025
    Review
  13. It's a match: use of the radionuclide theranostic pairEJNMMI radiopharmacy and chemistry · 2025
    Article
  14. Article
  15. Enhancing the Stability ofACS medicinal chemistry letters · 2025
    Article
  16. Article
  17. Review
  18. Lead-it-EAZY! GMP-compliant production of [EJNMMI radiopharmacy and chemistry · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bryce J B NelsonDepartment of Oncology, University of Alberta, 11560 University Ave., Edmonton, AB T6G 1Z2, Canada.ORCID 0000-0003-3735-303X
John WilsonDepartment of Oncology, University of Alberta, 11560 University Ave., Edmonton, AB T6G 1Z2, Canada.
Jan D AnderssonDepartment of Oncology, University of Alberta, 11560 University Ave., Edmonton, AB T6G 1Z2, Canada.ORCID 0000-0003-2593-884X
Frank WuestDepartment of Oncology, University of Alberta, 11560 University Ave., Edmonton, AB T6G 1Z2, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article highlights recent developments of SPECT and PET diagnostic imaging surrogates for targeted alpha particle therapy (TAT) radiopharmaceuticals. It outlines the rationale for using imaging surrogates to improve diagnostic-scan accuracy and facilitate research, and the properties an imaging-surrogate candidate should possess. It evaluates the strengths and limitations of each potential imaging surrogate. Thirteen surrogates for TAT are explored:

Indexed as

actinium-225alpha particle therapylanthanum-133lead-203lead-212PET imagingSPECT imagingtargeted alpha therapytargeted radionuclide therapytheranostics

Identifiers

PMID38004486
PMCPMC10674391

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.