Evidence map›Paper›PMID 38004363›Full record

ArticleLife (Basel, Switzerland)2023

Anterior Scleral Thickness Profile in Keratoconus.

Neus Burguera-Giménez, María Amparo Díez-Ajenjo, Noemí Burguera, Cristina Peris-Martínez

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Neus Burguera-GiménezAnterior Segment and Cornea and External Eye Diseases Unit, Foundation Ophthalmological Medical Hospital (FOM), Av. Pío Baroja, 12, E-46015 Valencia, Spain.ORCID 0000-0002-0508-1431
María Amparo Díez-AjenjoAnterior Segment and Cornea and External Eye Diseases Unit, Foundation Ophthalmological Medical Hospital (FOM), Av. Pío Baroja, 12, E-46015 Valencia, Spain.ORCID 0000-0002-8146-4039
Noemí BurgueraQ Vision, Ophthalmology Department, Vithas Virgen del Mar Hospital, Ctra. el Mami a Viator, Km.1, E-04120 Almería, Spain.
Cristina Peris-MartínezAnterior Segment and Cornea and External Eye Diseases Unit, Foundation Ophthalmological Medical Hospital (FOM), Av. Pío Baroja, 12, E-46015 Valencia, Spain.
Universitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeConsidering that peripheral corneal thinning occurs in keratoconus (KC), the anterior scleral thickness (AST) profile was measured to compare thickness variations in healthy and KC eyes across several meridians.

methodsThis cross-sectional case-control study comprised 111 eyes of 111 patients: 61 KC eyes and 50 age- and axial-length-matched healthy eyes. The AST was explored at three scleral eccentricities (1, 2, and 3 mm from the scleral spur) across four scleral zones (nasal, temporal, superior, and inferior) by using swept-source optical coherence tomography. The AST variations among eccentricities and scleral regions within and between groups were investigated.

resultsThe AST significantly varied with scleral eccentricity in healthy eyes over the temporal meridian (

conclusionsKC eyes presented significant thickness variations among eccentricities over the paracentral sclera. Although AST profiles did not differ between groups, the inferior-superior asymmetry differences demonstrated scleral changes over the vertical meridian in KC that need further investigation.

Indexed as

anterior scleral thicknessinferior–superior asymmetrykeratoconusscleraswept-source OCT

Identifiers

PMID38004363
PMCPMC10671989
OpenAlexW4388832158

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.