Evidence map›Paper›PMID 38004251›Full record

ArticleLife (Basel, Switzerland)2023

Risk of SARS-CoV-2 Reinfection 3 Years after the Start of the Pandemic: A Population-Level Observational Study.

Cecilia Acuti Martellucci, Maria Elena Flacco, Graziella Soldato, Giuseppe Di Martino, Roberto Carota, Annalisa Rosso, Marco De Benedictis, Graziano Di Marco, Rossano Di Luzio, Francesco Lisbona and 2 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Cecilia Acuti MartellucciDepartment of Environmental and Prevention Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-4308-2144
Maria Elena FlaccoDepartment of Environmental and Prevention Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-1404-4314
Graziella SoldatoLocal Health Unit of Pescara, 65124 Pescara, Italy.
Giuseppe Di MartinoLocal Health Unit of Pescara, 65124 Pescara, Italy.ORCID 0000-0001-7047-7611
Roberto CarotaLocal Health Unit of Pescara, 65124 Pescara, Italy.
Annalisa RossoDepartment of Environmental and Prevention Sciences, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-0537-5130
Marco De BenedictisLocal Health Unit of Pescara, 65124 Pescara, Italy.
Graziano Di MarcoLocal Health Unit of Pescara, 65124 Pescara, Italy.
Rossano Di LuzioLocal Health Unit of Pescara, 65124 Pescara, Italy.
Francesco LisbonaDepartment of Medical and Surgical Sciences, University of Bologna, 40100 Bologna, Italy.
Antonio CaponettiLocal Health Unit of Pescara, 65124 Pescara, Italy.
Lamberto ManzoliDepartment of Medical and Surgical Sciences, University of Bologna, 40100 Bologna, Italy.ORCID 0000-0002-8129-9344
Azienda USL di Pescara · ITUniversity of Ferrara · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The risk of SARS-CoV-2 reinfections changes as new variants emerge, but the follow-up time for most of the available evidence is shorter than two years. This study evaluated SARS-CoV-2 reinfection rates in the total population of an Italian province up to three years since the pandemic's start. This retrospective cohort study used official National Healthcare System data on SARS-CoV-2 testing and vaccinations, demographics, and hospitalizations in the Province of Pescara, Italy, from 2 March 2020 to 31 December 2022. A total of 6541 (5.4%) reinfections and 33 severe and 18 lethal COVID-19 cases were recorded among the 121,412 subjects who recovered from a primary infection. There were no severe events following reinfection in the young population, whereas 1.1% of reinfected elderly died. A significantly higher reinfection risk was observed among females; unvaccinated individuals; adults (30-59 y); and subjects with hypertension, COPD, and kidney disease. Up to three years after a primary SARS-CoV-2 infection, the majority of the population did not experience a reinfection. The risk of severe COVID-19 following a reinfection was very low for young and adult individuals but still high for the elderly. The subjects with hybrid immunity showed a lower reinfection risk than the unvaccinated.

Indexed as

case fatality rateCOVID-19reinfectionSARS-CoV-2vaccination

Identifiers

PMID38004251
PMCPMC10672528
OpenAlexW4387909393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.