Evidence map›Paper›PMID 38004206›Full record

Trial reportNutrients2023

Effects of an Unripe Avocado Extract on Glycaemic Control in Individuals with Obesity: A Double-Blinded, Parallel, Randomised Clinical Trial.

Lijun Zhao, Donald K Ingram, Eric Gumpricht, Trent De Paoli, Xiao Tong Teong, Bo Liu, Trevor A Mori, Leonie K Heilbronn, George S Roth

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Antiobesity Potential of Selected Latin American Edible Plants: A Review.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Lijun ZhaoAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-6134-5235
Donald K IngramPennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA.
Eric GumprichtIsagenix International LLC, Gilbert, AZ 85297, USA.ORCID 0000-0001-6034-3484
Trent De PaoliDe Paoli Farms, Bundaberg, QLD 4670, Australia.
Xiao Tong TeongAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-1387-0975
Bo LiuAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, Australia.
Trevor A MoriDiscipline of Internal Medicine, Medical School, University of Western Australia, Perth, WA 6000, Australia.ORCID 0000-0002-5264-9229
Leonie K HeilbronnAdelaide Medical School, The University of Adelaide, Adelaide, SA 5005, Australia.
George S RothProlongevity Technologies LLC, Pylesville, MD 21132, USA.
South Australian Health and Medical Research Institute · AUIndigenous Wellbeing Centre · AUPennington Biomedical Research Center · USThe University of Western Australia · AU

Funding

Isagenix (Asia Pacific) Australia Pty Ltd and CSIRO Innovations connections grant ICG UA194450
6 · The paper itself

Abstract

backgroundUnripe avocados (

objectivesTo evaluate the effects of a diet supplement made from unripe avocado on glucose tolerance, and cardiometabolic risk factors in free-living nondiabetic adults with obesity.

methodsIn a double-blinded, randomised controlled trial, 60 adults (female n = 47, age 48 ± 13 years, BMI 34.0 ± 2.6 kg/m

resultsThere were no between-group differences in glucose AUC (

conclusionsDaily consumption of unripe avocado extract enriched in MH did not alter glucose tolerance or insulin sensitivity in nondiabetic adults with obesity, but the data provided preliminary evidence for a benefit in insulin AUC in a subgroup of participants with elevated baseline postprandial insulin levels.

Indexed as

PerseaAdultBlood GlucoseFemaleGlucoseGlycemic ControlHumansInsulinMaleMiddle AgedObesityBlood GlucoseGlucoseInsulinautophagyavocadocardiovascular risk factorsglucoseinsulinmannoheptulose

Identifiers

PMID38004206
PMCPMC10674186
OpenAlexW4388775057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.