Evidence map›Paper›PMID 38004164›Full record

Observational studyNutrients2023

Redefining Nutritional Requirements in End-Stage Liver Disease: Towards a Personalized Approach.

Brooke Chapman, Darren Wong, Bethany Whitcher, Marie Sinclair, Paul Gow, Avik Majumdar, Adam Testro

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Addressing Malnutrition in Australian Hospitals: A Scoping Review to Inform Systems Thinking.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brooke ChapmanDepartment of Nutrition and Dietetics, Austin Health, Heidelberg, VIC 3084, Australia.ORCID 0000-0002-7251-8314
Darren WongLiver Transplant Unit, Austin Health, Heidelberg, VIC 3084, Australia.ORCID 0000-0003-1490-0547
Bethany WhitcherLiver Transplant Unit, Austin Health, Heidelberg, VIC 3084, Australia.
Marie SinclairLiver Transplant Unit, Austin Health, Heidelberg, VIC 3084, Australia.ORCID 0000-0003-0657-3048
Paul GowLiver Transplant Unit, Austin Health, Heidelberg, VIC 3084, Australia.
Avik MajumdarLiver Transplant Unit, Austin Health, Heidelberg, VIC 3084, Australia.
Adam TestroLiver Transplant Unit, Austin Health, Heidelberg, VIC 3084, Australia.
The University of Melbourne · AUAustin Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malnutrition is ubiquitous in cirrhotic patients presenting for liver transplant (LT). Providing an appropriate energy prescription is fundamental to effective nutrition therapy. We aimed to compare measured energy expenditure (mEE) with predicted energy expenditure (pEE) in patients awaiting LT and determine clinical factors associated with mEE. In this prospective observational study, energy expenditure was measured by indirect calorimetry in 110 adult patients referred for LT and predicted by commonly utilized equations (Harris-Benedict, Schofield, and EASL guidelines). Nutritional status, anthropometry, muscle function, biochemical and clinical data were also collected. The median model for end-stage liver disease (MELD) was 19 (IQR 13, 25), and the majority were Child-Pugh B (51%) or C (37%). Malnutrition was evident in 85%. Median mEE by calorimetry was 1756 (1531, 2104) kcal/d and significantly higher than pEE as per Harris-Benedict 1480 (1322, 1722) kcal/d and Schofield 1474 (1349, 1723) kcal/d (both

Indexed as

End Stage Liver DiseaseMalnutritionAdultCalorimetry, IndirectEnergy MetabolismHumansNutritional RequirementsSeverity of Illness Indexcirrhosisenergy requirementsindirect calorimetryliver transplantmalnutrition

Identifiers

PMID38004164
PMCPMC10675823
OpenAlexW4388630500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.