Evidence map›Paper›PMID 38004101›Full record

Trial reportNutrients2023

Dairy Intake Modifies the Level of the Bile Acid Precursor and Its Correlation with Serum Proteins Associated with Cholesterol Clearance in Subjects with Hyperinsulinemia.

Atena Mahdavi, Jocelyn Trottier, Olivier Barbier, Michel Lebel, Iwona Rudkowska

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Atena MahdaviEndocrinology and Nephrology, CHU de Québec Research Center-Université Laval, Quebec City, QC G1V 4G2, Canada.
Jocelyn TrottierLaboratory of Molecular Pharmacology, CHU de Québec Research Center-Université Laval, Quebec City, QC G1V 4G2, Canada.
Olivier BarbierLaboratory of Molecular Pharmacology, CHU de Québec Research Center-Université Laval, Quebec City, QC G1V 4G2, Canada.ORCID 0000-0002-3067-1134
Michel LebelEndocrinology and Nephrology, CHU de Québec Research Center-Université Laval, Quebec City, QC G1V 4G2, Canada.
Iwona RudkowskaEndocrinology and Nephrology, CHU de Québec Research Center-Université Laval, Quebec City, QC G1V 4G2, Canada.ORCID 0000-0003-2392-564X
Université Laval · CA

Funding

Michel Lebel and Iwona Rudkowska CIHR grant number: PJT-173398 to M.L. and PJT-364008 to I.R
6 · The paper itself

Abstract

Bile acids regulate glucose homeostasis and lipid metabolism. Further, the levels of bile acids can be influenced by the intake of dairy products. Although the serum proteome can provide information on the biological pathways associated with different metabolites, it is unknown whether the intake of dairy modifies such associations between bile acids and the proteome. The objectives of this study were to examine plasma bile acid profiles, find the correlations between bile acids and lipid as well as glycemic markers, and to uncover the correlation between bile acids and proteins after high dairy (HD) and adequate dairy (AD) intake among 25 overweight individuals with hyperinsulinemia. In this randomized crossover-trial study, hyperinsulinemia adults were randomized to both HD (≥4 servings/day) and AD (≤2 servings/day) for 6 weeks. Measurements and analyses were performed on before- as well as after- AD and HD conditions. The results indicated that plasma 7α-hydroxy-4-cholesten-3-one (7AC4) increased after HD in comparison with before HD intake (

Indexed as

Diabetes Mellitus, Type 2HyperinsulinismAdultBile Acids and SaltsBlood ProteinsCholesterolDairy ProductsHumansProteomeBile Acids and SaltsBlood ProteinsCholesterolProteomebile acids precursorcholesterol clearancedairy intakehyperinsulinemiaserum proteins

Identifiers

PMID38004101
PMCPMC10675775
OpenAlexW4388465161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.