Evidence map›Paper›PMID 38003863›Full record

ReviewJournal of personalized medicine2023

Vasopressin in Sepsis and Other Shock States: State of the Art.

Raquel García-Álvarez, Rafael Arboleda-Salazar

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06422975 (Prospective Multicentre Observational Study of Patients Treated With Vasopressin in Critical Care Units), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06422975 unknown statusnot on this mapstarted 2024, after this paper: background citation

Prospective Multicentre Observational Study of Patients Treated With Vasopressin in Critical Care Units

Typeobservational_patient_registrySponsorHospital Universitario 12 de OctubreRan2024 to 2026Enrolled500ConditionsVasopressin Causing Adverse Effects in Therapeutic Use, Shock, Vasopressor Adverse Reaction, Vasopressin DeficiencyArmsVasopressin
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Review
  7. Hemodynamic rescue after blast injury: intravenous administration outperforms intramuscular vasopressin in a swine model.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  8. Observational
  9. Review
  10. Observational
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Raquel García-ÁlvarezDepartment of Anesthesiology and Surgical Intensive Care, University Hospital 12 de Octubre, 28022 Madrid, Spain.ORCID 0000-0002-8813-1384
Rafael Arboleda-SalazarDepartment of Anesthesiology and Surgical Intensive Care, University Hospital 12 de Octubre, 28022 Madrid, Spain.
Research Institute Hospital 12 de Octubre · ES

Funding

Research Institute Hospital 12 de Octubre 2023/0107
6 · The paper itself

Abstract

This review of the use of vasopressin aims to be comprehensive and highly practical, based on the available scientific evidence and our extensive clinical experience with the drug. It summarizes controversies about vasopressin use in septic shock and other vasodilatory states. Vasopressin is a natural hormone with powerful vasoconstrictive effects and is responsible for the regulation of plasma osmolality by maintaining fluid homeostasis. Septic shock is defined by the need for vasopressors to correct hypotension and lactic acidosis secondary to infection, with a high mortality rate. The Surviving Sepsis Campaign guidelines recommend vasopressin as a second-line vasopressor, added to norepinephrine. However, these guidelines do not address specific debates surrounding the use of vasopressin in real-world clinical practice.

Indexed as

septic shockvasodilatory shockvasoplegiavasopressin

Identifiers

PMID38003863
PMCPMC10672256
OpenAlexW4388159921

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.