Evidence map›Paper›PMID 38003679›Full record

ArticleInternational journal of molecular sciences2023

Metabolic Markers and Association of Biological Sex in Lupus Nephritis.

Bethany Wolf, Calvin R K Blaschke, Sandy Mungaray, Bryan T Weselman, Mariia Stefanenko, Mykhailo Fedoriuk, Hongxia Bai, Jessalyn Rodgers, Oleg Palygin, Richard R Drake and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Glycosylation in kidney diseases.Precision clinical medicine · 2025
    Review
  3. Article
  4. Immune Mechanisms and Biomarkers in Systemic Lupus Erythematosus.International journal of molecular sciences · 2024
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bethany WolfDepartment of Public Health Sciences, Medical University of South Carolina, 135 Cannon Street, Suite 303 MSC 835, Charleston, SC 29425, USA.ORCID 0000-0002-7124-5158
Calvin R K BlaschkeDepartment of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, 173 Ashley Avenue Basic Science Building 358, Charleston, SC 29425, USA.
Sandy MungarayDivision of Rheumatology, Department of Medicine, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA.
Bryan T WeselmanDepartment of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, 173 Ashley Avenue Basic Science Building 358, Charleston, SC 29425, USA.ORCID 0000-0002-3214-5090
Mariia StefanenkoDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Clinical Sciences Building, 96 Jonathan Lucas Street, Charleston, SC 29425, USA.ORCID 0000-0003-2161-2842
Mykhailo FedoriukDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Clinical Sciences Building, 96 Jonathan Lucas Street, Charleston, SC 29425, USA.ORCID 0000-0003-0278-8519
Hongxia BaiDepartment of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, 173 Ashley Avenue Basic Science Building 358, Charleston, SC 29425, USA.
Jessalyn RodgersDivision of Rheumatology, Department of Medicine, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA.
Oleg PalyginDivision of Nephrology, Department of Medicine, Medical University of South Carolina, Clinical Sciences Building, 96 Jonathan Lucas Street, Charleston, SC 29425, USA.ORCID 0000-0002-3680-5527
Richard R DrakeDepartment of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, 173 Ashley Avenue Basic Science Building 358, Charleston, SC 29425, USA.
Tamara K NowlingDivision of Rheumatology, Department of Medicine, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA.ORCID 0000-0002-1445-5415
Medical University of South Carolina · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI John J Lemasters · 2009 to 2026
$42.7M
Resource CoreP30AR072582 · NIAMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JAMES C OATES · 2017 to 2026
$8.5M
RESEARCH PILOT PROJECTS PROGRAMP30GM103339 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OGRETMEN, BESIM · 2012 to 2016
$5.4M
Role of basolateral K channels in renal salt handling and BP controlR01DK126720 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PALYGIN, OLEG · 2021 to 2024
$1.5M
Renal diabetic complications mediated by the PAR1 signaling in podocytesR01DK129227 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI PALYGIN, OLEG, STARUSCHENKO, ALEXANDER · 2022 to 2025
$1.3M
Simplified Glycan Profiling Workflows of Captured Immune Glycoproteins and CellsU01CA242096 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ANGEL, PEGGI M, DRAKE, RICHARD R. · 2019 to 2021
$818k
NCI NIH HHS P30 CA138313NCI NIH HHS U01 CA242096NIAMS NIH HHS P30 AR072582NIDDK NIH HHS R01 DK126720NIDDK NIH HHS R01 DK129227NIGMS NIH HHS P30 GM103339NIH HHS DK126720, DK129227, CA242096
6 · The paper itself

Abstract

Lupus nephritis (LN) is a serious complication for many patients who develop systemic lupus erythematosus, which primarily afflicts women. Our studies to identify biomarkers and the pathogenic mechanisms underlying LN will provide a better understanding of disease progression and sex bias, and lead to identification of additional potential therapeutic targets. The glycosphingolipid lactosylceramide (LacCer) and N-linked glycosylated proteins (N-glycans) were measured in urine and serum collected from LN and healthy control (HC) subjects (10 females and 10 males in each group). The sera from the LN and HC subjects were used to stimulate cytokine secretion and intracellular Ca

Indexed as

Lupus Erythematosus, SystemicLupus NephritisBiomarkersCytokinesFemaleGlycosphingolipidsHumansMalePolysaccharidesBiomarkersCytokinesGlycosphingolipidsPolysaccharidesbiomarkerglycosphingolipidglycosylationlupus nephritismesangial cellN-glycansex bias

Identifiers

PMID38003679
PMCPMC10671813
OpenAlexW4388795758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.