Evidence map›Paper›PMID 38003580›Full record

ArticleInternational journal of molecular sciences2023

A Regulator Role for the ATP-Binding Cassette Subfamily C Member 6 Transporter in HepG2 Cells: Effect on the Dynamics of Cell-Cell and Cell-Matrix Interactions.

Ilenia Matera, Rocchina Miglionico, Vittorio Abruzzese, Giovanna Marchese, Giovanna Maria Ventola, Maria Antonietta Castiglione Morelli, Faustino Bisaccia, Angela Ostuni

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ilenia MateraDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0009-0007-7278-9839
Rocchina MiglionicoDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.
Vittorio AbruzzeseDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.
Giovanna MarcheseGenomix4Life Srl, 84081 Baronissi, Italy.
Giovanna Maria VentolaGenomix4Life Srl, 84081 Baronissi, Italy.
Maria Antonietta Castiglione MorelliDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0003-3967-3117
Faustino BisacciaDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.
Angela OstuniDepartment of Sciences, University of Basilicata, 85100 Potenza, Italy.ORCID 0000-0001-5970-5097
University of Basilicata · ITCenter for Genomic Science · IT

Funding

INBIOMED PROJECT MIUR, ARS01_01081
6 · The paper itself

Abstract

There is growing evidence that various ATP-binding cassette (ABC) transporters contribute to the growth and development of tumors, but relatively little is known about how the ABC transporter family behaves in hepatocellular carcinoma (HCC), one of the most common cancers worldwide. Cellular model studies have shown that ABCC6, which belongs to the ABC subfamily C (ABCC), plays a role in the cytoskeleton rearrangement and migration of HepG2 hepatocarcinoma cells, thus highlighting its role in cancer biology. Deep knowledge on the molecular mechanisms underlying the observed results could provide therapeutic insights into the tumors in which

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdenosine TriphosphateATP-Binding Cassette TransportersHep G2 CellsHumansAdenosine TriphosphateATP-Binding Cassette TransportersABCC6 silencingadhesionextracellular matrixHepG2 cellsinvasionmigrationtranscriptome analysis

Identifiers

PMID38003580
PMCPMC10670978
OpenAlexW4388726578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.