Evidence map›Paper›PMID 38003551›Full record

ArticleInternational journal of molecular sciences2023

Functional Characterization of Novel

Idris Mohammed, Senthil Selvaraj, Wesam S Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R Saraiva, Mashael Al-Shafai, Khalid Hussain

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Melanocortin 4 receptor mutation in obesity.World journal of experimental medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Idris MohammedCollege of Health & Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.ORCID 0000-0002-8983-0929
Senthil SelvarajDepartment of Disease Modeling and Therapeutics, Sidra Medicine, Doha P.O. Box 26999, Qatar.
Wesam S AhmedCollege of Health & Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.ORCID 0000-0002-3441-2631
Tara Al-BarazenjiDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Ayat S HammadDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Hajar DaulehDivision of Endocrinology, Department of Pediatric Medicine, Sidra Medicine, Doha P.O. Box 26999, Qatar.
Luis R SaraivaCollege of Health & Life Sciences, Hamad Bin Khalifa University, Doha P.O. Box 34110, Qatar.ORCID 0000-0003-4079-0396
Mashael Al-ShafaiDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Khalid HussainDivision of Endocrinology, Department of Pediatric Medicine, Sidra Medicine, Doha P.O. Box 26999, Qatar.ORCID 0000-0002-5480-7112
Hamad bin Khalifa University · QAQatar University · QA

Funding

Qatar National Research Fund [QNRF-NPRP 10-6100017-AXX]
6 · The paper itself

Abstract

The leptin-melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The

Indexed as

LeptinObesity, MorbidAllelesalpha-MSHHumansMutationQatarReceptor, Melanocortin, Type 4alpha-MSHLeptinMC4R protein, humanReceptor, Melanocortin, Type 4childhood obesityMC4Rmonogenic obesityQatarsevere obesity

Identifiers

PMID38003551
PMCPMC10671262
OpenAlexW4388699179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.