Evidence map›Paper›PMID 38003533›Full record

ArticleInternational journal of molecular sciences2023

Intravital Microscopy of Lipopolysaccharide-Induced Inflammatory Changes in Different Organ Systems-A Scoping Review.

Cassidy Scott, Daniel Neira Agonh, Hannah White, Saki Sultana, Christian Lehmann

Abstract readScoping Review
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Cells · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cassidy ScottDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS B3H1X5, Canada.ORCID 0000-0001-6780-3367
Daniel Neira AgonhDepartment of Physiology and Biophysics, Dalhousie University, Halifax, NS B3H1X5, Canada.
Hannah WhiteDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H1X5, Canada.
Saki SultanaDepartment of Pharmacology, Dalhousie University, Halifax, NS B3H1X5, Canada.ORCID 0000-0003-1929-0805
Christian LehmannDepartment of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS B3H1X5, Canada.ORCID 0000-0001-6419-9168

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravital microscopy (IVM) is a powerful imaging tool that captures biological processes in real-time. IVM facilitates the observation of complex cellular interactions in vivo, where ex vivo and in vitro experiments lack the physiological environment. IVM has been used in a multitude of studies under healthy and pathological conditions in different organ systems. IVM has become essential in the characterization of the immune response through visualization of leukocyte-endothelial interactions and subsequent changes within the microcirculation. Lipopolysaccharide (LPS), a common inflammatory trigger, has been used to induce inflammatory changes in various studies utilizing IVM. In this review, we provide an overview of IVM imaging of LPS-induced inflammation in different models, such as the brain, intestines, bladder, and lungs.

Indexed as

Intravital MicroscopyLipopolysaccharidesCell CommunicationEndotheliumIntestinesLeukocytesMicrocirculationLipopolysaccharidesinflammationintravital imagingleukocyteslipopolysaccharidemicrocirculation

Identifiers

PMID38003533
PMCPMC10671110

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.