Evidence map›Paper›PMID 38003531›Full record

ArticleInternational journal of molecular sciences2023

Tff3 Deficiency Differentially Affects the Morphology of Male and Female Intestines in a Long-Term High-Fat-Diet-Fed Mouse Model.

Kate Šešelja, Iva Bazina, Milka Vrecl, Jessica Farger, Martin Schicht, Friedrich Paulsen, Mirela Baus Lončar, Tatjana Pirman

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Anti-Atherogenic Activities of Exopolysaccharides and Their Producing StrainInternational journal of molecular sciences · 2026
    Article
  2. In Vivo Evaluation of the Effect ofInternational journal of molecular sciences · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Kate ŠešeljaDepartment of Molecular Medicine, Ruđer Bošković Institute, Bjenička 54, 10 000 Zagreb, Croatia.
Iva BazinaDepartment of Molecular Medicine, Ruđer Bošković Institute, Bjenička 54, 10 000 Zagreb, Croatia.
Milka VreclInstitute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, 1000 Ljubljana, Slovenia.ORCID 0000-0002-9968-9228
Jessica FargerInstitute of Functional and Clinical Anatomy, Faculty of Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.
Martin SchichtInstitute of Functional and Clinical Anatomy, Faculty of Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0001-5155-5477
Friedrich PaulsenInstitute of Functional and Clinical Anatomy, Faculty of Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0002-0527-0953
Mirela Baus LončarDepartment of Molecular Medicine, Ruđer Bošković Institute, Bjenička 54, 10 000 Zagreb, Croatia.ORCID 0000-0002-6940-2302
Tatjana PirmanDepartment of Animal Science, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7549-4488
Friedrich-Alexander-Universität Erlangen-Nürnberg · DERuđer Bošković Institute · HRUniversity of Ljubljana · SI

Funding

ROLE OF RENAL FAILURE IN AGE-ASSOCIATED CHANGES IN WISTAR RATSZ01AG000053 · NIA · AGING · PI FILBURN, C R · 1990 to 1990
–
Bilateral Croatian -Germany project of student exchange German project No. 57448642Croatian Science Foundation IP-06-2016-2717European Structural Found (financial support for Ph.D student) 2014-2020Slovenian Research Agency P4-0053Slovenian Research Agency P4-0097
6 · The paper itself

Abstract

Trefoil factor family protein 3 (Tff3) protects the gastrointestinal mucosa and has a complex mode of action in different tissues. Here, we aimed to determine the effect of Tff3 deficiency on intestinal tissues in a long-term high-fat-diet (HFD)-fed model. A novel congenic strain without additional metabolically relevant mutations (

Indexed as

Diet, High-FatProteinsAnimalsDuodenumFemaleMaleMiceMice, Inbred C57BLMice, Inbred StrainsTrefoil Factor-3ProteinsTrefoil Factor-3apoptosiscecumduodenumER stresshigh-fat dietinflammationoxidative stresstrefoil peptide 3

Identifiers

PMID38003531
PMCPMC10671422
OpenAlexW4388697743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.