Evidence map›Paper›PMID 38003529›Full record

ReviewInternational journal of molecular sciences2023

Peptoids: Smart and Emerging Candidates for the Diagnosis of Cancer, Neurological and Autoimmune Disorders.

Anna Giorgio, Annarita Del Gatto, Simone Pennacchio, Michele Saviano, Laura Zaccaro

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Pd(II)-Catalyzed Strategies for the β-Arylation of α-Amino Acids: An Overview.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Systematic Investigation on Acid-Catalyzed Truncation ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna GiorgioDepartment of Chemical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-5099-6967
Annarita Del GattoInstitute of Biostructure and Bioimaging (IBB), CNR, 80131 Naples, Italy.ORCID 0000-0003-2879-8635
Simone PennacchioInstitute of Condensed Matter Chemistry and Technologies for Energy (ICMATE), CNR, 35127 Padova, Italy.ORCID 0009-0003-8347-5086
Michele SavianoInstitute of Crystallography (IC), CNR, 70126 Bari, Italy.ORCID 0000-0001-5086-2459
Laura ZaccaroInstitute of Biostructure and Bioimaging (IBB), CNR, 80131 Naples, Italy.ORCID 0000-0001-6843-0152

Funding

Italian Association for Cancer Research 24528
6 · The paper itself

Abstract

Early detection of fatal and disabling diseases such as cancer, neurological and autoimmune dysfunctions is still desirable yet challenging to improve quality of life and longevity. Peptoids (N-substituted glycine oligomers) are a relatively new class of peptidomimetics, being highly versatile and capable of mimicking the architectures and the activities of the peptides but with a marked resistance to proteases and a propensity to cross the cellular membranes over the peptides themselves. For these properties, they have gained an ever greater interest in applications in bioengineering and biomedical fields. In particular, the present manuscript is to our knowledge the only review focused on peptoids for diagnostic applications and covers the last decade's literature regarding peptoids as tools for early diagnosis of pathologies with a great impact on human health and social behavior. The review indeed provides insights into the peptoid employment in targeted cancer imaging and blood-based screening of neurological and autoimmune diseases, and it aims to attract the scientific community's attention to continuing and sustaining the investigation of these peptidomimetics in the diagnosis field considering their promising peculiarities.

Indexed as

Autoimmune DiseasesNeoplasmsPeptidomimeticsPeptoidsHumansPeptidesQuality of LifePeptidesPeptidomimeticsPeptoidsautoimmune diseaseblood-based screeningcancerdiagnosisneurological diseasepeptoidstargeted imaging

Identifiers

PMID38003529
PMCPMC10671428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.