Evidence map›Paper›PMID 38003521›Full record

ArticleInternational journal of molecular sciences2023

Naphthyl-Substituted Indole and Pyrrole Carboxylic Acids as Effective Antibiotic Potentiators-Inhibitors of Bacterial Cystathionine γ-Lyase.

Andrey S Kuzovlev, Mikhail D Zybalov, Andrey V Golovin, Maxim A Gureev, Mariia A Kasatkina, Mikhail V Biryukov, Albina R Belik, Sergey A Silonov, Maxim A Yunin, Nailya A Zigangirova and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Effect of HArchives of microbiology · 2024
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Andrey S KuzovlevTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.ORCID 0000-0002-4952-3561
Mikhail D ZybalovTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.ORCID 0009-0000-0379-3446
Andrey V GolovinFaculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 1/73 Leninskie gori St., 119234 Moscow, Russia.
Maxim A GureevLaboratory of Bioinformatics, Center of AI and Information Technologies, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.ORCID 0000-0002-0385-922X
Mariia A KasatkinaTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Mikhail V BiryukovTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Albina R BelikTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Sergey A SilonovTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Maxim A YuninTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.ORCID 0000-0002-6866-8934
Nailya A ZigangirovaMedical Microbiology Department, Laboratory of Chlamydiosis, National Research Center for Epidemiology and Microbiology Named after N. F. Gamaleya, 18 Gamaleya St., 123098 Moscow, Russia.
Vasiliy V ReshetnikovTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.ORCID 0000-0002-2932-0804
Yulia E IsakovaTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Yuri B PorozovLaboratory of Bioinformatics, Center of AI and Information Technologies, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.
Roman A IvanovTranslational Medicine Research Center, Sirius University of Science and Technology, Olympic Ave. 1, 354340 Sochi, Russia.ORCID 0000-0002-9573-4183

Funding

Ministry of Science and Higher Education of the Russian Federation agreement № 075-10-2021-113, unique project ID RF----193021X0001
6 · The paper itself

Abstract

Over the past decades, the problem of bacterial resistance to most antibiotics has become a serious threat to patients' survival. Nevertheless, antibiotics of a novel class have not been approved since the 1980s. The development of antibiotic potentiators is an appealing alternative to the challenging process of searching for new antimicrobials. Production of H

Indexed as

Hydrogen SulfideMethicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsBacteriaCystathionine beta-SynthaseCystathionine gamma-LyaseHumansIndolesMolecular Docking SimulationPyrrolesAnti-Bacterial AgentsCystathionine beta-SynthaseCystathionine gamma-LyaseHydrogen SulfideIndolesPyrrolesantibiotic resistanceantibioticsCSEcystathionine γ-lyaseindolemolecular dockingmolecular dynamicsnaphthalenepotentiatorspyrrole

Identifiers

PMID38003521
PMCPMC10671052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.