Evidence map›Paper›PMID 38003498›Full record

ArticleInternational journal of molecular sciences2023

Analysis of the Polymorphisms and Expression Levels of the BCL2, BAX and c-MYC Genes in Patients with Ovarian Cancer.

Piotr Józef Olbromski, Anna Bogacz, Marta Bukowska, Adam Kamiński, Rafał Moszyński, Piotr Pawlik, Anna Szeliga, Katarzyna Kotrych, Bogusław Czerny

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. In Silico and Wet Analysis ofCurrent issues in molecular biology · 2025
    Article
  6. Article
  7. Clinicopathological insights and prognostic implications of DEK in association with apoptosis-regulating factors in ovarian cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  8. The Role of Functional Polymorphisms of ApoptoticIranian journal of medical sciences · 2025
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Piotr Józef OlbromskiClinic of Operational Gynecology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Anna BogaczDepartment of Personalized Medicine and Cell Therapy, Regional Blood Center, Marcelińska 44, 60-354 Poznan, Poland.ORCID 0000-0001-5455-8315
Marta BukowskaDepartment of Personalized Medicine and Cell Therapy, Regional Blood Center, Marcelińska 44, 60-354 Poznan, Poland.
Adam KamińskiDepartment of Orthopedics and Traumatology, Independent Public Clinical Hospital No. 1, Pomeranian Medical University, UniiLubelskiej 1, 71-252 Szczecin, Poland.
Rafał MoszyńskiDepartment of Gynecology, Obstetrics and Gynecological Oncology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.ORCID 0000-0001-5121-5026
Piotr PawlikClinic of Operational Gynecology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Anna SzeligaDepartment of Gynecological Endocrinology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.
Katarzyna KotrychDepartment of General and Dental Radiology, Pomeranian Medical University in Szczecin, al. Powstańców Wielkopolskch 72, 70-111 Szczecin, Poland.
Bogusław CzernyDepartment of Pharmacology and Pharmacoeconomics, Pomeranian Medical University in Szczecin, Żołnierska 48, 71-230 Szczecin, Poland.
Poznan University of Medical Sciences · PLPomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) is one of the biggest problems in gynecological oncology and is one of the most lethal cancers in women worldwide. Most patients with OC are diagnosed at an advanced stage; therefore, there is an urgent need to find new biomarkers for this disease. Gene expression profiling is proving to be a very effective tool for exploring new molecular markers for OC patients, although the relationship between such markers and patient survival and clinical outcomes is still elusive. Moreover, polymorphisms in genes encoding both apoptosis-associated proteins and oncoproteins may serve as key markers of cancer susceptibility. The aim of our study was to analyze the polymorphisms and expressions of the

Indexed as

Ovarian NeoplasmsProto-Oncogene Proteins c-bcl-2Apoptosis Regulatory Proteinsbcl-2-Associated X ProteinFemaleGenes, mycGenotypeHumansPolymorphism, Single NucleotideRNA, MessengerApoptosis Regulatory Proteinsbcl-2-Associated X ProteinBCL2 protein, humanProto-Oncogene Proteins c-bcl-2RNA, Messengerbiomarkersgene expressionindividualized therapyovarian cancerprotein expressionsingle-nucleotide polymorphism

Identifiers

PMID38003498
PMCPMC10671037
OpenAlexW4388684036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.