Evidence map›Paper›PMID 38003431›Full record

ReviewInternational journal of molecular sciences2023

CRISPR Variants for Gene Editing in Plants: Biosafety Risks and Future Directions.

Ali Movahedi, Soheila Aghaei-Dargiri, Hongyan Li, Qiang Zhuge, Weibo Sun

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali MovahediDepartment of Biology and the Environment, College of Life Sciences, Nanjing Forestry University, Nanjing 210037, China.ORCID 0000-0001-5062-504X
Soheila Aghaei-DargiriDepartment of Biological Control Research, Iranian Research Institute of Plant Protection, Agricultural Research Education and Extension Organization (AREEO), Tehran 19858-13111, Iran.ORCID 0000-0001-8674-266X
Hongyan LiDepartment of Biology and the Environment, College of Life Sciences, Nanjing Forestry University, Nanjing 210037, China.
Qiang ZhugeDepartment of Biology and the Environment, College of Life Sciences, Nanjing Forestry University, Nanjing 210037, China.ORCID 0000-0002-9450-487X
Weibo SunDepartment of Biology and the Environment, College of Life Sciences, Nanjing Forestry University, Nanjing 210037, China.

Funding

Weibo Sun CX2019030
6 · The paper itself

Abstract

The CRISPR genome editing technology is a crucial tool for enabling revolutionary advancements in plant genetic improvement. This review shows the latest developments in CRISPR/Cas9 genome editing system variants, discussing their benefits and limitations for plant improvement. While this technology presents immense opportunities for plant breeding, it also raises serious biosafety concerns that require careful consideration, including potential off-target effects and the unintended transfer of modified genes to other organisms. This paper highlights strategies to mitigate biosafety risks and explores innovative plant gene editing detection methods. Our review investigates the international biosafety guidelines for gene-edited crops, analyzing their broad implications for agricultural and biotechnology research and advancement. We hope to provide illuminating and refined perspectives for industry practitioners and policymakers by evaluating CRISPR genome enhancement in plants.

Indexed as

CRISPR-Cas SystemsGene EditingContainment of BiohazardsCrops, AgriculturalGenome, PlantPlant BreedingPlants, Genetically ModifiedbiosafetyCRISPR variantsgene editingoff-target effectsplant genetic improvement

Identifiers

PMID38003431
PMCPMC10671001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.