Evidence map›Paper›PMID 38003346›Full record

ArticleInternational journal of molecular sciences2023

Non-Invasive Physical Plasma Reduces the Inflammatory Response in Microbially Prestimulated Human Gingival Fibroblasts.

Benedikt Eggers, Matthias Bernhard Stope, Jana Marciniak, Alexander Mustea, Sigrun Eick, James Deschner, Marjan Nokhbehsaim, Franz-Josef Kramer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Benedikt EggersDepartment of Oral, Maxillofacial and Plastic Surgery, University Hospital Bonn, 53111 Bonn, Germany.ORCID 0000-0002-4274-3801
Matthias Bernhard StopeDepartment of Gynecology and Gynecological Oncology, University Hospital Bonn, 53127 Bonn, Germany.
Jana MarciniakDepartment of Orthodontics, University Hospital Bonn, 53111 Bonn, Germany.
Alexander MusteaDepartment of Gynecology and Gynecological Oncology, University Hospital Bonn, 53127 Bonn, Germany.
Sigrun EickDepartment of Periodontology, School of Dental Medicine, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0002-4619-2461
James DeschnerDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, 55131 Mainz, Germany.
Marjan NokhbehsaimSection of Experimental Dento-Maxillo-Facial Medicine, University Hospital Bonn, 53111 Bonn, Germany.ORCID 0000-0003-0998-1717
Franz-Josef KramerDepartment of Oral, Maxillofacial and Plastic Surgery, University Hospital Bonn, 53111 Bonn, Germany.
University Hospital Bonn · DEJohannes Gutenberg University Mainz · DEUniversity of Bern · CH

Funding

BONFOR O-133.0001
6 · The paper itself

Abstract

Non-invasive physical plasma (NIPP), an electrically conductive gas, is playing an increasingly important role in medicine due to its antimicrobial and regenerative properties. However, NIPP is not yet well established in dentistry, although it has promising potential, especially for periodontological applications. The aim of the present study was to investigate the effect of NIPP on a commercially available human gingival fibroblast (HGF) cell line and primary HGFs in the presence of periodontitis-associated bacteria. First, primary HGFs from eight patients were characterised by immunofluorescence, and cell numbers were examined by an automatic cell counter over 5 days. Then, HGFs that were preincubated with

Indexed as

Interleukin-6PeriodontitisCells, CulturedCytokinesFibroblastsGingivaHumansInterleukin-8CytokinesInterleukin-6Interleukin-8antimicrobial effectcold plasmadentistrygingival fibroblastsinflammationnon-invasive physical plasmanon-thermal plasmaperiodontology

Identifiers

PMID38003346
PMCPMC10671174
OpenAlexW4388569008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.