Evidence map›Paper›PMID 38003328›Full record

ArticleInternational journal of molecular sciences2023

Host Genetic Background Effect on Body Weight Changes Influenced by Heterozygous

Nayrouz Qahaz, Iqbal M Lone, Aya Khadija, Aya Ghnaim, Osayd Zohud, Nadav Ben Nun, Aysar Nashef, Imad Abu El-Naaj, Fuad A Iraqi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Biology · 2024
    Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nayrouz QahazDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.
Iqbal M LoneDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0001-5292-6778
Aya KhadijaDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.
Aya GhnaimDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.
Osayd ZohudDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0003-3530-1420
Nadav Ben NunDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.
Aysar NashefDepartment of Oral and Maxillofacial Surgery, Baruch Padeh Medical Center, Poriya 15208, Israel.
Imad Abu El-NaajDepartment of Oral and Maxillofacial Surgery, Baruch Padeh Medical Center, Poriya 15208, Israel.
Fuad A IraqiDepartment of Clinical Microbiology and Immunology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0001-5525-206X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and its attendant conditions have become major health problems worldwide, and obesity is currently ranked as the fifth most common cause of death globally. Complex environmental and genetic factors are causes of the current obesity epidemic. Diet, lifestyle, chemical exposure, and other confounding factors are difficult to manage in humans. The mice model is helpful in researching genetic BW gain because genetic and environmental risk factors can be controlled in mice. Studies in mouse strains with various genetic backgrounds and established genetic structures provide unparalleled opportunities to find and analyze trait-related genomic loci. In this study, we used the Collaborative Cross (CC), a large panel of recombinant inbred mouse strains, to present a predictive study using heterozygous

Indexed as

Collaborative Cross MiceObesityAnimalsBody WeightFemaleHumansMaleMiceMice, Inbred C57BLMice, Inbred StrainsMice, KnockoutSmad4 ProteinSmad4 ProteinSmad4 protein, mousebody weight gainCollaborative Cross (CC)genotypingmachine learning (ML)Smad4 knockout

Identifiers

PMID38003328
PMCPMC10671513

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.