Evidence map›Paper›PMID 38003196›Full record

ArticleAnimals : an open access journal from MDPI2023

The Use of Isoflurane and Adjunctive Magnesium Chloride Provides Fast, Effective Anaesthetization of

Anna Di Cosmo, Valeria Maselli, Emanuela Cirillo, Mariangela Norcia, Heethaka K S de Zoysa, Gianluca Polese, William Winlow

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Stress Induced by Fishing in Common Octopus (Animals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Anna Di CosmoDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.
Valeria MaselliDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0002-1452-8063
Emanuela CirilloDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.
Mariangela NorciaDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.
Heethaka K S de ZoysaDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-6425-7356
Gianluca PoleseDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0002-6322-7769
William WinlowDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-9465-802X
University of Naples Federico II · ITUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A wide variety of substances have been used to anaesthetise invertebrates, but many are not anaesthetics and merely incapacitate animals rather than preventing pain. In essence, the role of an ideal general anaesthetic is to act as a muscle relaxant, an analgesic, an anaesthetic, and an amnesic. To achieve all these properties with a single substance is difficult, and various adjuvants usually need to be administered, resulting in a cocktail of drugs. In a clinical setting, the vast majority of patients are unaware of surgery being carried out and have no memory of it, so they can claim to have felt no pain, but this is much more difficult to demonstrate in invertebrates. Here, we show that 1% MgCl

Indexed as

depth of anaesthesiageneral anaestheticsisofluranemagnesium chlorideOctopus vulgarisstress reduction

Identifiers

PMID38003196
PMCPMC10668643
OpenAlexW4388823627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.