Evidence map›Paper›PMID 38003129›Full record

ArticleAnimals : an open access journal from MDPI2023

Toward Renewable-Based Prebiotics from Woody Biomass: Potential of Tailored Xylo-Oligosaccharides Obtained by Enzymatic Hydrolysis of Beechwood Xylan as a Prebiotic Feed Supplement for Young Broilers.

Ines Dieryck, Winnie Dejonghe, Wouter Van Hecke, Joy Delacourt, An Bautil, Christophe M Courtin, Daniel Vermeulen, Johan Buyse, Jan Paeshuyse

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ines DieryckLaboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0003-2807-7678
Winnie DejongheFlemish Institute for Technological Research, 2400 Mol, Belgium.ORCID 0000-0003-2773-4226
Wouter Van HeckeFlemish Institute for Technological Research, 2400 Mol, Belgium.ORCID 0000-0002-8140-4562
Joy DelacourtLaboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.
An BautilLaboratory of Food Chemistry and Biochemistry, Department of Microbial and Molecular Systems, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0001-7034-187X
Christophe M CourtinLaboratory of Food Chemistry and Biochemistry, Department of Microbial and Molecular Systems, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-1203-9063
Daniel VermeulenLaboratory of Livestock Physiology, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.
Johan BuyseLaboratory of Livestock Physiology, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.
Jan PaeshuyseLaboratory of Host Pathogen Interactions, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0003-2396-354X

Funding

Research Foundation - Flanders S003518N
6 · The paper itself

Abstract

Although antibiotic resistance emerges naturally, this process has been accelerated by the worldwide overuse and misuse of antibiotics. It is essential to find effective alternatives in the broiler industry to improve poultry health while maintaining production efficiency and product safety. In this study, we aimed to evaluate a potential alternative: wood-derived xylo-oligosaccharides (XOS). The objective of this research was to investigate the potential of XOS prepared using enzymatic hydrolysis of beechwood xylan as a prebiotic feed supplement for broilers. A pilot study was conducted to explore the optimal XOS fraction profile by in vitro fermentation. Subsequently, a semi-continuous enzyme membrane reactor was used, allowing for the production of tailored XOS in large quantities. Given the strong bidirectional relationship between intestinal health, nutrition, and intestinal microbiota composition in broilers, an in vivo experiment was performed to explore the potential of XOS as a prebiotic feed supplement by investigating growth performance, feed conversion ratio, caecal short and medium chain fatty acid (SCFA and MCFA) concentration, and microbiological composition of the caecal content. Results from the pilot study indicated that higher enzyme concentrations in the hydrolysis process yield a product that leads to a higher total SCFA and MCFA- and butyric acid production during in vitro fermentation by caecal bacteria. Supplementation of the tailored XOS to the broiler diet (day 1 (d1)-d8 0.13%

Indexed as

broilersenzymatic hydrolysisprebioticsshort chain fatty acid analysisxylo-oligosaccharides

Identifiers

PMID38003129
PMCPMC10668712

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.