Evidence map›Paper›PMID 38003027›Full record

ArticleGenes2023

Association of a Single Nucleotide Variant in

Takashi Higuchi, Shomi Oka, Hiroshi Furukawa, Kota Shimada, Shinichiro Tsunoda, Satoshi Ito, Akira Okamoto, Misuzu Fujimori, Tadashi Nakamura, Masao Katayama and 6 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Multi-omics insights into the mechanisms and prognosis of IPF.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Takashi HiguchiDepartment of Clinical Research, NHO Tokyo National Hospital, 3-1-1 Takeoka, Kiyose 204-8585, Japan.
Shomi OkaDepartment of Clinical Research, NHO Tokyo National Hospital, 3-1-1 Takeoka, Kiyose 204-8585, Japan.
Hiroshi FurukawaDepartment of Clinical Research, NHO Tokyo National Hospital, 3-1-1 Takeoka, Kiyose 204-8585, Japan.ORCID 0000-0003-1353-8056
Kota ShimadaDepartment of Rheumatology, NHO Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku, Sagamihara 252-0392, Japan.
Shinichiro TsunodaDivision of Rheumatology, Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.
Satoshi ItoDepartment of Rheumatology, Niigata Rheumatic Center, 1-2-8 Hon-cho, Shibata 957-0054, Japan.
Akira OkamotoDepartment of Rheumatology, NHO Himeji Medical Center, 68 Hon-machi, Himeji 670-8520, Japan.
Misuzu FujimoriDepartment of Rheumatology, NHO Himeji Medical Center, 68 Hon-machi, Himeji 670-8520, Japan.
Tadashi NakamuraDepartment of Rheumatology, Sakurajyuji Hospital, 1-1-1 Miyukikibe, Minami-ku, Kumamoto 861-4173, Japan.
Masao KatayamaDepartment of Internal Medicine, NHO Nagoya Medical Center, 4-1-1 Sannomaru, Naka-ku, Nagoya 460-0001, Japan.
Koichiro SaishoDepartment of Orthopedics/Rheumatology, NHO Miyakonojo Medical Center, 5033-1 Iwayoshi-cho, Miyakonojo 885-0014, Japan.
Satoshi ShinoharaTochigi Rheumatology Clinic, 1-1-9 Ekimaedori, Utsunomiya 321-0964, Japan.ORCID 0000-0001-8850-0859
Toshihiro MatsuiClinical Research Center for Allergy and Rheumatology, NHO Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku, Sagamihara 252-0392, Japan.
Kiyoshi MigitaClinical Research Center, NHO Nagasaki Medical Center, 2-1001-1 Kubara, Omura 856-8562, Japan.
Shouhei NagaokaDepartment of Rheumatology, Yokohama Minami Kyosai Hospital, 1-21-1 Rokuura-higashi, Kanazawa-ku, Yokohama 236-0037, Japan.
Shigeto TohmaDepartment of Clinical Research, NHO Tokyo National Hospital, 3-1-1 Takeoka, Kiyose 204-8585, Japan.
National Sagamihara Hospital · JPHimeji Medical Center · JPFukushima Medical University · JPHyogo Medical University · JPImamura Hospital · JPInstitute for Rheumatic Diseases (Japan) · JPNagoya Medical Center · JPTokyo National Hospital · JPUji Hospital · JPYokohama Minami Kyosai Hospital · JP

Funding

Abbott Japan Co. LtdAstellas Pharma Inc.Bristol-Myers K.K.Bristol-Myers Squibb Co.Chugai Pharmaceutical Co., Ltd.Daiwa Securities Health FoundationEisai Co. Ltd.Japan Agency for Medical Research and DevelopmentJapan Research Foundation for Clinical PharmacologyMerck Sharp and Dohme Inc.Mitsubishi Tanabe Pharma CorporationMitsui Sumitomo Insurance Welfare FoundationNational Hospital OrganizationPfizer Japan Inc.Takeda Pharmaceutical Company LimitedTakeda Science FoundationTeijin Pharma Limitedthe Japan Society for the Promotion of Science 26293123, 22591090, 15K09543, 18K08402the Ministry of Health, Labour, and Welfare of JapanThe Nakatomi Foundation
6 · The paper itself

Abstract

Interstitial lung disease and airway disease (AD) are often complicated with rheumatoid arthritis (RA) and have a poor prognosis. Several studies reported genetic associations with interstitial lung disease in RA. However, few genetic studies have examined the susceptibility to AD in RA patients. Here, we investigated whether single nucleotide variants susceptible to idiopathic pulmonary fibrosis might be associated with interstitial lung disease or AD in Japanese RA patients. Genotyping of rs2736100 [C/A] in

Indexed as

Arthritis, RheumatoidIdiopathic Pulmonary FibrosisLung Diseases, InterstitialTelomeraseAgedEast Asian PeopleHumansNucleotidesNucleotidesTelomeraseTERT protein, humanairway diseasegenetic associationnonspecific interstitial pneumoniarheumatoid arthritissingle nucleotide variant

Identifiers

PMID38003027
PMCPMC10671651
OpenAlexW4388733980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.