Evidence map›Paper›PMID 38003026›Full record

ArticleGenes2023

Selective Sweeps in Cattle Genomes in Response to the Influence of Urbanization and Environmental Contamination.

Silpa Mullakkalparambil Velayudhan, Shahin Alam, Tong Yin, Kerstin Brügemann, Andreas Buerkert, Veerasamy Sejian, Raghavendra Bhatta, Eva Schlecht, Sven König

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Silpa Mullakkalparambil VelayudhanInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Giessen, Germany.ORCID 0000-0001-8078-4789
Shahin AlamAnimal Husbandry in the Tropics and Subtropics, University of Kassel and Georg-August-Universität Göttingen, Steinstr. 19, 37213 Witzenhausen, Germany.ORCID 0000-0003-2678-3245
Tong YinInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Giessen, Germany.
Kerstin BrügemannInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Giessen, Germany.ORCID 0000-0001-7532-8906
Andreas BuerkertOrganic Plant Production and Agroecosystems Research in the Tropics and Subtropics, University of Kassel, 37213 Witzenhausen, Germany.ORCID 0000-0003-1329-1559
Veerasamy SejianNational Institute of Animal Nutrition and Physiology (NIANP), Hosur Rd, Chennakeshava Nagar, Adugodi, Bengaluru 560030, India.ORCID 0000-0002-8224-4521
Raghavendra BhattaNational Institute of Animal Nutrition and Physiology (NIANP), Hosur Rd, Chennakeshava Nagar, Adugodi, Bengaluru 560030, India.ORCID 0000-0001-5074-185X
Eva SchlechtAnimal Husbandry in the Tropics and Subtropics, University of Kassel and Georg-August-Universität Göttingen, Steinstr. 19, 37213 Witzenhausen, Germany.ORCID 0000-0002-5420-2893
Sven KönigInstitute of Animal Breeding and Genetics, Justus-Liebig-University Gießen, Ludwigstraße 21 b, 35390 Giessen, Germany.ORCID 0000-0003-4226-3696
Justus-Liebig-Universität Gießen · DEUniversity of Kassel · DENational Institute of Animal Nutrition and Physiology · IN

Funding

Deutsche Forschungsgemeinschaft KO 3520/5-2
6 · The paper itself

Abstract

A genomic study was conducted to identify the effects of urbanization and environmental contaminants with heavy metals on selection footprints in dairy cattle populations reared in the megacity of Bengaluru, South India. Dairy cattle reared along the rural-urban interface of Bengaluru with/without access to roughage from public lakeshores were selected. The genotyped animals were subjected to the cross-population-extended haplotype homozygosity (XP-EHH) methodology to infer selection sweeps caused by urbanization (rural, mixed, and urban) and environmental contamination with cadmium and lead. We postulated that social-ecological challenges contribute to mechanisms of natural selection. A number of selection sweeps were identified when comparing the genomes of cattle located in rural, mixed, or urban regions. The largest effects were identified on BTA21, displaying pronounced peaks for selection sweeps for all three urbanization levels (urban_vs_rural, urban_vs_mixed and rural_vs_mixed). Selection sweeps are located in chromosomal segments in close proximity to the genes lrand rab interactor 3 (

Indexed as

CadmiumUrbanizationAnimalsCattleGenomeGenotypeSelection, GeneticCadmiumadaptationdairy cattleenvironmental contaminantsselection signatureurbanization

Identifiers

PMID38003026
PMCPMC10671461
OpenAlexW4388699356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.