Evidence map›Paper›PMID 38002992›Full record

ArticleGenes2023

Uncoupling Protein 3 Promotes the Myogenic Differentiation of Type IIb Myotubes in C2C12 Cells.

Ziwei You, Jieyu Wang, Faliang Li, Wei Hei, Meng Li, Xiaohong Guo, Pengfei Gao, Guoqing Cao, Chunbo Cai, Bugao Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ziwei YouCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.ORCID 0000-0002-6411-1987
Jieyu WangCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Faliang LiCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Wei HeiCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Meng LiCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Xiaohong GuoCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Pengfei GaoCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Guoqing CaoCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Chunbo CaiCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Bugao LiCollege of Animal Science, Shanxi Agricultural University, 1 Mingxian Nanlu, Jinzhong 030801, China.
Shanxi Agricultural University · CN

Funding

National Natural Science Foundation of China 32272846the key research and development project of Shanxi Province 202102140601005the Shanxi Agricultural University science & technology innovation and promotion project CXGC2023014
6 · The paper itself

Abstract

Uncoupling protein 3 (Ucp3) is an important transporter within mitochondria and is mainly expressed in skeletal muscle, brown adipose tissue and the myocardium. However, the effects of Ucp3 on myogenic differentiation are still unclear. This study evaluated the effects of Ucp3 on myogenic differentiation, myofiber type and energy metabolism in C2C12 cells. Gain- and loss-of-function studies revealed that

Indexed as

Muscle Fibers, SkeletalMyosin Heavy ChainsCell DifferentiationCell LineUncoupling Protein 3Myosin Heavy ChainsUncoupling Protein 3C2C12 cellsenergy metabolismmyogenic differentiationtypes of myotubesUcp3

Identifiers

PMID38002992
PMCPMC10671304
OpenAlexW4388452937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.