Evidence map›Paper›PMID 38002841›Full record

ArticleChildren (Basel, Switzerland)2023

Children and Young People with Long COVID-Comparing Those Seen in Post-COVID Services with a Non-Hospitalised National Cohort: A Descriptive Study.

Fiona Newlands, Anne-Lise Goddings, Maude Juste, Holly Boyd, Manjula D Nugawela, Snehal M Pinto Pereira, Emily Whelan, Elizabeth Whittaker, Terence Stephenson, Isobel Heyman and 5 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Fiona NewlandsGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.ORCID 0000-0003-3078-7281
Anne-Lise GoddingsGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Maude JusteGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Holly BoydUniversity College London Hospitals NHS Foundation Trust, London NW1 2BU, UK.
Manjula D NugawelaGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.ORCID 0000-0001-5989-9530
Snehal M Pinto PereiraDivision of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London WC1E 6BT, UK.ORCID 0000-0002-0876-8757
Emily WhelanSchool of Psychology, University of Sussex, Brighton BN1 9QH, UK.ORCID 0000-0003-1862-7453
Elizabeth WhittakerDepartment of Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London W2 1NY, UK.
Terence StephensonGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Isobel HeymanGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.
Trudie ChalderInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.ORCID 0000-0003-0775-1045
Emma DalrympleGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.ORCID 0000-0002-6645-932X
CLoCk Consortium
Terry SegalUniversity College London Hospitals NHS Foundation Trust, London NW1 2BU, UK.ORCID 0000-0002-4420-8810
Roz ShafranGreat Ormond Street Institute of Child Health, University College London, London WC1N 1EH, UK.ORCID 0000-0003-2729-4961
University College London · GBUniversity College London Hospitals NHS Foundation Trust · GBImperial College Healthcare NHS Trust · GBKing's College London · GBUniversity of Sussex · GB

Funding

Medical Research Council MR/P020372/1
6 · The paper itself

Abstract

backgroundPost-COVID services have been set up in England to treat children with ongoing symptoms of Long COVID. To date, the characteristics of children seeking treatment from these services has not been described. PURPOSE: (1) to describe the characteristics of children aged 11-17 referred to the Pan-London Post-COVID service and (2) to compare characteristics of these children with those taking part in the United Kingdom's largest research study of Long COVID in children (CLoCk).

designData from 95 children seeking treatment from the Post-COVID service between May 2021 and August 2022 were included in the study. Their demographic characteristics, symptom burden and the impact of infection are described and compared to children from CLoCk.

resultsA high proportion of children from the Post-COVID service and CLoCk reported experiencing health problems prior to the pandemic. Almost all Post-COVID service children met the research Delphi definition of Long COVID (94.6%), having multiple symptoms that impacted their lives. Symptoms were notably more severe than the participants in CLoCk.

conclusionsThis study describes the characteristics of children seeking treatment for Long COVID compared to those identified in the largest longitudinal observational study to date. Post-COVID service children have more symptoms and are more severely affected by their symptoms following infection with COVID-19 than children in the CLoCk study. Research to understand predisposing factors for severity and prognostic indicators is essential to prevent this debilitating condition. Evaluation of short- and long-term outcomes of interventions by clinical services can help direct future therapy for this group.

Indexed as

children and young peopleLong COVIDpaediatricPost-COVID servicesSARS-CoV-2

Identifiers

PMID38002841
PMCPMC10670307
OpenAlexW4388105260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.