Evidence map›Paper›PMID 38002648›Full record

ArticleJournal of clinical medicine2023

Structural and Functional Retinal Changes in Patients with Mild Cognitive Impairment with and without Diabetes.

Álvaro Santos-Ortega, Carmen Alba-Linero, Facundo Urbinati, Carlos Rocha-de-Lossada, Rafael Orti, José Antonio Reyes-Bueno, Francisco Javier Garzón-Maldonado, Vicente Serrano, Carmen de Rojas-Leal, Carlos de la Cruz-Cosme and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Álvaro Santos-OrtegaDepartment of Ophthalmology, Hospital Costa del Sol, 29603 Malaga, Spain.
Carmen Alba-LineroDepartment of Ophthalmology, Hospital Universitario Virgen de la Victoria, 29010 Malaga, Spain.
Facundo UrbinatiDepartment of Ophthalmology, Hospital Regional Universitario, 29011 Malaga, Spain.
Carlos Rocha-de-LossadaDepartment of Ophthalmology, Hospital Regional Universitario, 29011 Malaga, Spain.ORCID 0000-0001-7464-2493
Rafael OrtiDepartment of Ophthalmology, Faculty of Medicine, University of Malaga, 29016 Malaga, Spain.
José Antonio Reyes-BuenoDepartment of Neurology, Hospital Regional Universitario, 29011 Malaga, Spain.
Francisco Javier Garzón-MaldonadoDepartment of Neurology, Hospital Virgen de la Victoria, 29010 Malaga, Spain.ORCID 0000-0002-7591-3213
Vicente SerranoDepartment of Neurology, Hospital Virgen de la Victoria, 29010 Malaga, Spain.
Carmen de Rojas-LealDepartment of Neurology, Hospital Virgen de la Victoria, 29010 Malaga, Spain.
Carlos de la Cruz-CosmeDepartment of Neurology, Hospital Virgen de la Victoria, 29010 Malaga, Spain.
Manuela España-ContrerasDepartment of Ophthalmology, Hospital Regional Universitario, 29011 Malaga, Spain.
Marina Rodríguez-Calvo-de-MoraDepartment of Ophthalmology, Hospital Regional Universitario, 29011 Malaga, Spain.
Natalia García-CasaresInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Malaga, Spain.ORCID 0000-0003-4861-6966
Hospital Clínico Universitario Virgen de la Victoria · ESHospital Regional Universitario de Málaga · ESHospital Costa del Sol · ESInstituto de Investigación Biomédica de Málaga · ESUniversidad de Málaga · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective is to analyze retinal changes using optical coherence tomography angiography (OCT-A) in patients with mild cognitive impairment (MCI) to characterize structural and vascular alterations. This cross-sectional study involved 117 eyes: 39 eyes from patients with MCI plus diabetes (DM-MCI), 39 eyes from patients with MCI but no diabetes (MCI); and 39 healthy control eyes (C). All patients underwent a visual acuity measurement, a structural OCT, an OCT-A, and a neuropsychological examination. Our study showed a thinning of retinal nerve fiber layer thickness (RNFL) and a decrease in macular thickness when comparing the MCI-DM group to the C group (

Indexed as

Alzheimer’s diseasediabetesmild cognitive impairmentoptical coherence tomography angiography

Identifiers

PMID38002648
PMCPMC10672424
OpenAlexW4388637917

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.