Evidence map›Paper›PMID 38002646›Full record

ReviewJournal of clinical medicine2023

Can Machine Learning Models Detect and Predict Lymph Node Involvement in Prostate Cancer? A Comprehensive Systematic Review.

Eliodoro Faiella, Federica Vaccarino, Raffaele Ragone, Giulia D'Amone, Vincenzo Cirimele, Claudia Lucia Piccolo, Daniele Vertulli, Rosario Francesco Grasso, Bruno Beomonte Zobel, Domiziana Santucci

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eliodoro FaiellaRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Federica VaccarinoRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.ORCID 0000-0003-0472-0526
Raffaele RagoneRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.ORCID 0009-0006-6110-6134
Giulia D'AmoneRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Vincenzo CirimeleRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Claudia Lucia PiccoloRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Daniele VertulliRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.ORCID 0000-0002-7301-1670
Rosario Francesco GrassoRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.
Bruno Beomonte ZobelRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.ORCID 0000-0001-9227-5535
Domiziana SantucciRadiology Department, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Roma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Recently, Artificial Intelligence (AI)-based models have been investigated for lymph node involvement (LNI) detection and prediction in Prostate cancer (PCa) patients, in order to reduce surgical risks and improve patient outcomes. This review aims to gather and analyze the few studies available in the literature to examine their initial findings. (2) Methods: Two reviewers conducted independently a search of MEDLINE databases, identifying articles exploring AI's role in PCa LNI. Sixteen studies were selected, and their methodological quality was appraised using the Radiomics Quality Score. (3) Results: AI models in Magnetic Resonance Imaging (MRI)-based studies exhibited comparable LNI prediction accuracy to standard nomograms. Computed Tomography (CT)-based and Positron Emission Tomography (PET)-CT models demonstrated high diagnostic and prognostic results. (4) Conclusions: AI models showed promising results in LN metastasis prediction and detection in PCa patients. Limitations of the reviewed studies encompass retrospective design, non-standardization, manual segmentation, and limited studies and participants. Further research is crucial to enhance AI tools' effectiveness in this area.

Indexed as

artificial intelligencelymph nodesmachine learningprostate cancerradiomics

Identifiers

PMID38002646
PMCPMC10672480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.