Evidence map›Paper›PMID 38002637›Full record

ArticleJournal of clinical medicine2023

Histocompatibility Leukocyte Antigen-A29-Associated Retinal Vasculitis without Choroidal Lesions: A Report of 4 Cases.

Estefanía Ramírez-Márquez, Sofía C Ayala Rodríguez, Alejandra Santiago, Edgar De Jesus, Guillermo A Requejo Figueroa, Mona M Riskalla, Meghan E Ryan, Dara Koozekanani, Armando L Oliver

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Estefanía Ramírez-MárquezDepartment of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, USA.
Sofía C Ayala RodríguezDepartment of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, USA.ORCID 0000-0002-1221-9822
Alejandra SantiagoDepartment of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, USA.
Edgar De JesusDepartment of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, USA.
Guillermo A Requejo FigueroaDepartment of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, USA.
Mona M RiskallaDivision of Pediatric Rheumatology, Allergy, and Immunology, Department of Pediatrics, University of Minnesota Medical School Twin Cities, Minneapolis, MN 55455, USA.
Meghan E RyanDivision of Pediatric Rheumatology, Allergy, and Immunology, Department of Pediatrics, University of Minnesota Medical School Twin Cities, Minneapolis, MN 55455, USA.
Dara KoozekananiDepartment of Ophthalmology and Visual Neurosciences, University of Minnesota Medical School Twin Cities, Minneapolis, MN 55455, USA.
Armando L OliverDepartment of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PR 00936, USA.ORCID 0000-0001-7533-6121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes a cohort of patients presenting with histocompatibility leukocyte antigen (HLA)-A29-associated retinal vasculitis without choroidal lesions that may share clinical features with birdshot retinochoroiditis. The methods include a retrospective chart review of patients presenting with HLA-A29-associated retinal vasculitis without choroidal lesions. The data on the patients were entered retrospectively into a new database and analyzed. Four patients who had HLA-A29-associated retinal vasculitis without choroidal lesions were identified. The median age at presentation was 40 years (range: 14-71); 75% were female. At presentation, all four patients had a visual acuity of 20/50 or better in both eyes. All the eyes had mild vitritis, three eyes (37.5%) had cystoid macular edema, and two eyes (25%) had optic disc edema. All the patients required treatment with systemic steroids and immunosuppressive therapy. HLA-A29-associated retinal vasculitis without choroidal lesions appears to share many clinical features with birdshot chorioretinitis, including the need for systemic immunosuppressive therapy. Whether this entity represents an early form of birdshot retinochoroiditis or a more localized variant of the disease is a topic for additional studies.

Indexed as

birdshot retinochoroidopathyHLA-A29retinal vasculitis

Identifiers

PMID38002637
PMCPMC10672558

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.