Evidence map›Paper›PMID 38002567›Full record

ArticleBrain sciences2023

EEG Changes during Propofol Anesthesia Induction in Vegetative State Patients Undergoing Spinal Cord Stimulation Implantation Surgery.

Xuewei Qin, Xuanling Chen, Bo Wang, Xin Zhao, Yi Tang, Lan Yao, Zhenhu Liang, Jianghong He, Xiaoli Li

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xuewei QinDepartment of Anesthesiology, Peking University International Hospital, Beijing 102206, China.ORCID 0009-0009-5261-8287
Xuanling ChenDepartment of Anesthesiology, Peking University International Hospital, Beijing 102206, China.
Bo WangDepartment of Anesthesiology, Peking University International Hospital, Beijing 102206, China.
Xin ZhaoDepartment of Anesthesiology, Peking University International Hospital, Beijing 102206, China.
Yi TangDepartment of Anesthesiology, Peking University International Hospital, Beijing 102206, China.
Lan YaoDepartment of Anesthesiology, Peking University International Hospital, Beijing 102206, China.
Zhenhu LiangInstitute of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China.
Jianghong HeDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Xiaoli LiState Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China.ORCID 0000-0003-1359-5130
Peking University · CNBeijing Normal University · CNCapital Medical University · CNYanshan University · CN

Funding

STI2030-Major Projects 2021ZD0204300
6 · The paper itself

Abstract

objectiveTo compare the EEG changes in vegetative state (VS) patients and non-craniotomy, non-vegetative state (NVS) patients during general anesthesia with low-dose propofol and to find whether it affects the arousal rate of VS patients.

methodsSeven vegetative state patients (VS group: five with traumatic brain injury, two with ischemic-hypoxic VS) and five non-craniotomy, non-vegetative state patients (NVS group) treated in the Department of Neurosurgery, Peking University International Hospital from January to May 2022 were selected. All patients were induced with 0.5 mg/kg propofol, and the Bispectral Index (BIS) changes within 5 min after administration were observed. Raw EEG signals and perioperative EEG signals were collected and analyzed using EEGLAB in the MATLAB software environment, time-frequency spectrums were calculated, and EEG changes were analyzed using power spectrums.

resultsThere was no significant difference in the general data before surgery between the two groups (

conclusionsLow doses of propofol cause great differences in the EEG of different types of VS patients, which may be the unique response of damaged nerve cell residual function to propofol, and these weak responses may also be the basis of brain recovery.

Indexed as

bispectral indexelectroencephalogrampower spectrumpropofoltime–frequency spectrumvegetative state

Identifiers

PMID38002567
PMCPMC10669685
OpenAlexW4388823860

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.