Evidence map›Paper›PMID 38002536›Full record

ArticleBrain sciences2023

Psychophysiological and Neurophysiological Correlates of Dropping Objects from Hands in Carpal Tunnel Syndrome.

Gianluca Isoardo, Eugenia Rota, Stefano Ciullo, Paolo Titolo, Enrico Matteoni, Ilaria Stura, Andrea Calvo, Elena Fontana, Bruno Battiston, Giuseppe Migliaretti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Gianluca IsoardoDepartment of Neurosciences & Mental Health, Hospital "Città della Salute e della Scienza di Torino", 10126 Turin, Italy.
Eugenia RotaNeurology Unit, San Giacomo Hospital, Novi Ligure, ASL Alessandria, 15121 Alessandria, Italy.ORCID 0000-0003-3154-7634
Stefano CiulloDepartment of Psychology, University of Turin, 10124 Turin, Italy.
Paolo TitoloUOD Reconstructive Microsurgery, Department of Orthopedics & Traumatology, Hospital "Città della Salute e della Scienza di Torino", 10126 Turin, Italy.
Enrico Matteoni'Rita Levi Montalcini' Department of Neuroscience, University of Turin, 10126 Turin, Italy.ORCID 0009-0008-2963-8821
Ilaria Stura'Rita Levi Montalcini' Department of Neuroscience, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-9815-5446
Andrea Calvo'Rita Levi Montalcini' Department of Neuroscience, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-5122-7243
Elena FontanaDepartment of Psychology, University of Turin, 10124 Turin, Italy.
Bruno BattistonUOD Reconstructive Microsurgery, Department of Orthopedics & Traumatology, Hospital "Città della Salute e della Scienza di Torino", 10126 Turin, Italy.
Giuseppe MigliarettiDepartment of Public Health and Pediatric Sciences, University of Torino, 10126 Torino, Italy.
Rita B ArditoDepartment of Psychology, University of Turin, 10124 Turin, Italy.ORCID 0000-0002-5020-6598
Mauro AdenzatoDepartment of Psychology, University of Turin, 10124 Turin, Italy.ORCID 0000-0002-6997-9283
University of Turin · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITOspedale San Giacomo Apostolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDropping objects from hands (DOH) is a common symptom of carpal tunnel syndrome (CTS). We evaluated the clinical, neurophysiological, and psychophysiological features of 120 CTS patients to elucidate the DOH pathophysiology. Forty-nine healthy controls were included.

methodsIn the patients, the Boston Carpal Tunnel Questionnaire (BCTQ), the Douleur Neuropathique 4 questions (DN4), and a numeric rating scale for pain (NRS) were evaluated. In patients and controls, we evaluated bilateral median and ulnar motor and sensory nerve conduction studies, cutaneous silent period and cutaneomuscular reflexes (CMR) of the abductor pollicis brevis, cold-detection threshold (CDT) and heat-pain detection threshold (HPT) at the index, little finger, and dorsum of the hand, and vibratory detection threshold at the index and little finger by quantitative sensory testing.

resultsCTS with DOH had higher BCTQ, DN4 and NRS, lower median sensory action potential, longer CMR duration, lower CDT and higher HPT at all tested sites than controls and CTS without DOH. Predictive features for DOH were abnormal CDT and HPT at the right index and dorsum (OR: 3.88,

conclusionsThermal hypoesthesia in median and extra-median innervated territories and neuropathic pain are predictive of DOH in CTS.

Indexed as

carpal tunnel syndromecutaneomuscular reflexescutaneous silent periodneuropathic painquantitative sensory testing

Identifiers

PMID38002536
PMCPMC10670400
OpenAlexW4388568017

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.