Evidence map›Paper›PMID 38002359›Full record

ArticleBiomolecules2023

Effects of Combinations of Untranslated-Region Sequences on Translation of mRNA.

Anna Kirshina, Olga Vasileva, Dmitry Kunyk, Kristina Seregina, Albert Muslimov, Roman Ivanov, Vasiliy Reshetnikov

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anna KirshinaTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Olga VasilevaTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Dmitry KunykTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Kristina SereginaTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.
Albert MuslimovTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.ORCID 0000-0001-5736-2764
Roman IvanovTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.ORCID 0000-0002-9573-4183
Vasiliy ReshetnikovTranslational Medicine Research Center, Sirius University of Science and Technology, 354340 Sochi, Russia.ORCID 0000-0002-2932-0804
Sirius University of Science and Technology · RU

Funding

Ministry of Science and Higher Education of the Russian Federation agreement No. 075-10-2021-113, unique project ID RF-193021 × 0001
6 · The paper itself

Abstract

mRNA-based therapeutics have been found to be a promising treatment strategy in immunotherapy, gene therapy, and cancer treatments. Effectiveness of mRNA therapeutics depends on the level and duration of a desired protein's expression, which is determined by various

Indexed as

Protein Biosynthesis3' Untranslated Regions5' Untranslated RegionsAnimalsLuciferasesMiceRabbitsRNA, MessengerTransfection3' Untranslated Regions5' Untranslated RegionsLuciferasesRNA, Messenger3′UTR5′UTRmRNA therapeuticsRNA stabilitytranslation efficiency

Identifiers

PMID38002359
PMCPMC10669451
OpenAlexW4388823645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.