Evidence map›Paper›PMID 38002266›Full record

ArticleBiomolecules2023

Namodenoson Inhibits the Growth of Pancreatic Carcinoma via Deregulation of the Wnt/β-catenin, NF-κB, and RAS Signaling Pathways.

Inbal Itzhak, Avital Bareket-Samish, Pnina Fishman

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06387342 (CF102-222PC), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06387342 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

CF102-222PC: A Phase 2 Open-Label Study of the Safety and Activity of Namodenoson in the Treatment of Advanced Pancreatic Adenocarcinoma

TypeinterventionalSponsorCan-Fite BioPharmaRan2024 to 2026Enrolled20ConditionsPancreatic Adenocarcinoma, Pancreatic CancerArmsNamodenoson 25mg
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. 2-Substituted (N)-Methanocarba AACS pharmacology & translational science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Inbal ItzhakCan-Fite BioPharma, Petah Tikva 49170, Israel.
Avital Bareket-SamishBioInsight, Binyamina 3056814, Israel.
Pnina FishmanCan-Fite BioPharma, Petah Tikva 49170, Israel.
Can-Fite BioPharma (Israel) · IL

Funding

Can-Fite BioPharma (Israel) NA
6 · The paper itself

Abstract

Namodenoson, an A

Indexed as

NF-kappa BPancreatic NeoplasmsAnimalsApoptosisbeta CateninCell Line, TumorCell ProliferationMiceMice, NudeSignal Transductionbeta CateninNF-kappa BA3AR agonistapoptosismechanism of actionnamodenosonpancreatic cancerRASWnt/β-catenin

Identifiers

PMID38002266
PMCPMC10669398
OpenAlexW4387975097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.