Evidence map›Paper›PMID 38002085›Full record

ArticleBiomedicines2023

An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches.

Ali Irfan, Shah Faisal, Sajjad Ahmad, Muhammad Jawwad Saif, Ameer Fawad Zahoor, Samreen Gul Khan, Jamila Javid, Sami A Al-Hussain, Muhammed Tilahun Muhammed, Magdi E A Zaki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8977-3303
Shah FaisalDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.ORCID 0000-0002-5105-6982
Sajjad AhmadDepartment of Health and Biological Sciences, Abasyn University Peshawar, Peshawar 25000, Pakistan.ORCID 0000-0003-0754-1742
Muhammad Jawwad SaifDepartment of Applied Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-9589-876X
Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0003-2127-8848
Samreen Gul KhanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.
Jamila JavidDepartment of Chemistry, University of Sialkot, Sialkot 51040, Pakistan.
Sami A Al-HussainDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13623, Saudi Arabia.
Muhammed Tilahun MuhammedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Suleyman Demirel University, Isparta 32260, Turkey.ORCID 0000-0003-0050-5271
Magdi E A ZakiDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13623, Saudi Arabia.ORCID 0000-0002-5643-9202

Funding

: This research was supported by the Deanship of Scientific Research, Imam Mohammad Ibn Saud Islamic University (IMSIU), Saudi Arabia 000
6 · The paper itself

Abstract

Benzofuran, 1,3,4-oxadiazole, and 1,2,4-triazole are privileged heterocyclic moieties that display the most promising and wide spectrum of biological activities against a wide variety of diseases. In the current study, benzofuran-1,3,4-oxadiazole

Indexed as

ADMET studiesbenzofuran derivativesDFT studiesenergy decomposition analysishepatitis CMD simulationsMM-PBSAmolecular dockingRdRp NS5B inhibitorsSAR

Identifiers

PMID38002085
PMCPMC10669698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.