Evidence map›Paper›PMID 38002075›Full record

ArticleBiomedicines2023

Preparation, Physicochemical Characterization, Antimicrobial Effects, Biocompatibility and Cytotoxicity of Co-Loaded Meropenem and Vancomycin in Mesoporous Silica Nanoparticles.

Mina Yekani, Robab Azargun, Simin Sharifi, Javid Sadri Nahand, Alka Hasani, Hadi Ghanbari, Zahra Sadat Seyyedi, Mohammad Yousef Memar, Solmaz Maleki Dizaj

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mina YekaniInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.
Robab AzargunMedicinal Plants Research Center, Maragheh University of Medical Science, Maragheh 55158-78151, Iran.
Simin SharifiDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.ORCID 0000-0002-3020-3779
Javid Sadri NahandInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.
Alka HasaniImmunology Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.
Hadi GhanbariDepartment of Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.ORCID 0000-0003-1580-3829
Zahra Sadat SeyyediDepartment of Microbiology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan 87137-83976, Iran.
Mohammad Yousef MemarInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.
Solmaz Maleki DizajDental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz 51548-53431, Iran.ORCID 0000-0003-4759-7222

Funding

Tabriz University of Medical Sciences 66760
6 · The paper itself

Abstract

Mesoporous silica nanoparticles (MSNPs) have been reported as an effective system to co-deliver a variety of different agents to enhance efficiency and improve biocompatibility. This study was aimed at the preparation, physicochemical characterization, antimicrobial effects, biocompatibility, and cytotoxicity of vancomycin and meropenem co-loaded in the mesoporous silica nanoparticles (Van/Mrp-MSNPs). The prepared nanoparticles were explored for their physicochemical features, antibacterial and antibiofilm effects, biocompatibility, and cytotoxicity. The minimum inhibitory concentrations (MICs) of the Van/Mrp-MSNPs (0.12-1 µg/mL) against

Indexed as

co-deliverymeropenemmesoporous silica nanoparticlesmethicillin-resistant Staphylococcus aureusvancomycin

Identifiers

PMID38002075
PMCPMC10669092

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.