Evidence map›Paper›PMID 38002018›Full record

ArticleBiomedicines2023

The Efficacy and Safety of Intrasphincteric Botulinum Toxin-A Injections in Patients with Non-Spinal Cord Injury-Related Detrusor Sphincter Dyssynergia: A Retrospective Study.

Kilian Röthlin, Ralf Anding, Helge Seifert, Margret Hund-Georgiadis, Sandra Möhr, Matthias Walter

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kilian RöthlinDepartment of Urology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.
Ralf AndingDepartment of Urology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.ORCID 0000-0001-5020-3445
Helge SeifertDepartment of Urology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.ORCID 0000-0003-1443-9316
Margret Hund-GeorgiadisClinic of Neurorehabilitation and Paraplegiology, REHAB Basel, 4055 Basel, Switzerland.ORCID 0000-0002-4415-2888
Sandra MöhrNeuro-Urology, REHAB Basel, 4055 Basel, Switzerland.ORCID 0000-0001-8843-0846
Matthias WalterDepartment of Urology, University Hospital Basel, University of Basel, 4031 Basel, Switzerland.ORCID 0000-0001-5347-1584
University of Basel · CHSwiss Paraplegic Center · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botulinum toxin-A (BoNT-A) injections into the external urethral sphincter are an established therapeutic procedure for reducing bladder outlet obstruction in patients with detrusor sphincter dyssynergia (DSD) due to spinal cord injury (SCI). Given the paucity of data on patients with DSD but without SCI, we aimed to assess the efficacy of intrasphincteric BoNT-A injections in this cohort. For this retrospective study, we screened all patients who underwent their first intrasphincteric BoNT-A injection at our institution between 2015 and 2021. The inclusion criteria were patients aged 18 years or older with neurogenic detrusor overactivity (NDO) and DSD with a maximum detrusor pressure (Pdetmax) of >40 cmH

Indexed as

botulinum toxin-Adetrusor sphincter dyssynergiaelectromyographyexternal urethral sphincternon-spinal cord injury

Identifiers

PMID38002018
PMCPMC10669099
OpenAlexW4388567866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.