Evidence map›Paper›PMID 38002011›Full record

ArticleBiomedicines2023

Relationship between the Ubiquitin-Proteasome System and Autophagy in Colorectal Cancer Tissue.

Martyna Bednarczyk, Małgorzata Muc-Wierzgoń, Sylwia Dzięgielewska-Gęsiak, Dariusz Waniczek

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Martyna BednarczykDepartment of Hematology and Cancer Prevention, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Małgorzata Muc-WierzgońDepartment of Preventive Medicine, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0001-6562-7072
Sylwia Dzięgielewska-GęsiakDepartment of Preventive Medicine, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0003-1019-5959
Dariusz WaniczekDepartment of Surgical Nursing and Propaedeutics of Surgery, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0002-0410-8604
Medical University of Silesia · PL

Funding

Medical University of Silesia KNW/0022/KB1/42/14.
6 · The paper itself

Abstract

backgroundDysregulation of the autophagy process via ubiquitin is associated with the occurrence of a number of diseases, including cancer. The present study analyzed the changes in the transcriptional activity of autophagy-related genes and the ubiquitination process (UPS) in colorectal cancer tissue. (2) Methods: The process of measuring the transcriptional activity of autophagy-related genes was analyzed by comparing colorectal cancer samples from four clinical stages I-IV (CS I-IV) of adenocarcinoma to the control (C). The transcriptional activity of genes associated with the UPS pathway was determined via the microarray technique (HG-U133A, Affymetrix). (3) Results: Of the selected genes, only

Indexed as

autophagycolorectal cancer tissueubiquitin–proteasome system

Identifiers

PMID38002011
PMCPMC10669458
OpenAlexW4388523638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.