ReviewBiomedicines2023
Chorioamnionitis: An Update on Diagnostic Evaluation.
Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 26 citations in OpenAlex.
- Maternal infection in the context of actively managed prelabor rupture of membranes at term: An observational study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Observational
- Article
- Serum Neutrophil Gelatinase-Associated Lipocalin, Total Oxidant Status, and Total Antioxidant Status in Preterm Infants Following Clinical Chorioamnionitis or Preterm Premature Rupture of Membranes: A Multicenter Prospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- RAGE-Mediated Signalling in Gynaecological Disorders: Review of Molecular Mechanisms and Therapeutic Perspectives.Expert reviews in molecular medicine · 2026Review
- Early Prediction Model for Retinopathy of Prematurity Using Placental and Neonatal Risk Factors.Investigative ophthalmology & visual science · 2026Article
- Delayed residual intra-abdominal abscess with threatened preterm labor after laparoscopic appendectomy in the second trimester.Journal of surgical case reports · 2026Article
- Prevalence and associated factors of chorioamnionitis among women with preterm premature rupture of membranes at Mbarara Regional Referral Hospital, Southwestern Uganda.BMC pregnancy and childbirth · 2026Article
- Serum amyloid A as a diagnostic marker for histologic chorioamnionitis in preterm premature rupture of membranes: A diagnostic accuracy study.International journal of reproductive biomedicine · 2026Article
- Association between maternal cervical Ureaplasma urealyticum colonization and adverse perinatal outcomes: a prospective multicenter cohort study.BMC pregnancy and childbirth · 2026Article
- The association of chorioamnionitis with intraventricular hemorrhage and long-term outcome in very preterm neonates.Frontiers in pediatrics · 2026Article
- Chorioamnionitis in the Second Trimester Secondary to Multidrug-ResistantCase reports in infectious diseases · 2026Article
- Conservative management leading to delivery of a twin pregnancy complicated by previable preterm premature rupture of membranes: a case report.AME case reports · 2026Article
- Association between placental histological chorioamnionitis and respiratory distress syndrome in preterm infants: a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Research Progress on perinatalFrontiers in microbiology · 2026Review
- The Role of the Vaginal Microbiome in Preterm Premature Rupture of Membranes: A Comprehensive Review of Mechanisms and Clinical Implications.Health science reports · 2025Article
- Treatment strategies for intra-amniotic infection and/or inflammation in preterm labor cases.European journal of obstetrics & gynecology and reproductive biology: X · 2025Article
- Article
- Maternal bacteremia in intrapartum fever: the role of ampicillin resistance and prolonged membrane rupture-a retrospective comparative study.Archives of gynecology and obstetrics · 2025Article
- High-sensitivity CRP is elevated in pregnant women with overweight and obesity and modulated by gestational weight gain.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Infection-Related Preterm Birth.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2025Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chorioamnionitis remains a major cause of preterm birth and maternal and neonatal morbidity. We reviewed the current evidence for the diagnostic tests of chorioamnionitis and how this relates to clinical practice today. A comprehensive literature search and review was conducted on chorioamnionitis and intra-uterine inflammation. Data from randomized control trials and systematic reviews were prioritized. This review highlights that sterile inflammation plays an important role in chorioamnionitis and that the current tests for chorioamnionitis including clinical criteria, maternal plasma and vaginal biomarkers lack diagnostic accuracy. Concerningly, these tests often rely on detecting an inflammatory response after damage has occurred to the fetus. Care should be taken when interpreting current investigations for the diagnosis of chorioamnionitis and how they guide obstetric/neonatal management. There is an urgent need for further validation of current diagnostic tests and the development of novel, accurate, minimally invasive tests that detect subclinical intra-uterine inflammation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.