Evidence map›Paper›PMID 38001908›Full record

ArticleBiomedicines2023

From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients.

Benedicte Grebstad Tune, Heena Sareen, Branka Powter, Smadar Kahana-Edwin, Adam Cooper, Eng-Siew Koh, Cheok S Lee, Joseph W Po, Geoff McCowage, Mark Dexter and 11 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 2 countries.

Benedicte Grebstad TuneDepartment of Pediatric Research, Division of Paediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.
Heena SareenCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.ORCID 0000-0003-0671-0663
Branka PowterCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.
Smadar Kahana-EdwinChildren's Cancer Research Unit, Kids Research, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.ORCID 0000-0002-2869-4310
Adam CooperCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.
Eng-Siew KohSouth Western Sydney Clinical School, University of New South Wales, Goulburn St, Liverpool, NSW 2170, Australia.
Cheok S LeeSchool of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Joseph W PoCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.
Geoff McCowageCancer Centre for Children, The Children Hospital at Westmead, Westmead, NSW 2145, Australia.
Mark DexterNeurosurgery, The Children Hospital at Westmead, Westmead, NSW 2145, Australia.
Lucy CainCancer Centre for Children, The Children Hospital at Westmead, Westmead, NSW 2145, Australia.ORCID 0000-0002-1734-2707
Geraldine O'NeillChildren's Cancer Research Unit, Kids Research, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Victoria PriorChildren's Cancer Research Unit, Kids Research, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Jonathan KarpelowskyChildren's Cancer Research Unit, Kids Research, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
Maria TsoliChildren's Cancer Institute, Randwick, NSW 2031, Australia.
Lars O BaumbuschDepartment of Pediatric Research, Division of Paediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, 0372 Oslo, Norway.ORCID 0000-0003-1290-312X
David ZieglerChildren's Cancer Institute, Randwick, NSW 2031, Australia.ORCID 0000-0001-7451-7916
Tara L RobertsCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.ORCID 0000-0001-9266-0943
Paul DeSouzaCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.
Therese M BeckerCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.ORCID 0000-0002-5636-9902
Yafeng MaCentre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 1 Campbell St, Liverpool, NSW 2170, Australia.ORCID 0000-0002-0522-8771
Camden and Campbelltown Hospitals · AUChildren's Hospital at Westmead · AUThe University of Sydney · AUIngham Institute · AUOslo University Hospital · NOUNSW Sydney · AUChildren's Cancer Institute Australia · AULiverpool Hospital · AU

Funding

Wellcome Trust 220006
6 · The paper itself

Abstract

Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by

Indexed as

adult gliomachildhood brain cancercirculating free DNA (cfDNA)circulating tumor DNA (ctDNA)droplet digital PCR (ddPCR)glioblastomahistone mutations

Identifiers

PMID38001908
PMCPMC10669073
OpenAlexW4387971135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.