Evidence map›Paper›PMID 38001887›Full record

ArticleBiomedicines2023

Impact of COVID-19 on Pregnancy Outcomes across Trimesters in the United States.

Shiza Virk, Karthik Gangu, Adeel Nasrullah, Aaisha Shah, Zohaa Faiz, Umair Khan, David Bradley Jackson, Anam Javed, Asif Farooq, Briana DiSilvio and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. COVID-19 Vaccine Literacy Among Black Pregnant and Postpartum Women in the USA.Journal of racial and ethnic health disparities · 2026
    Article
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  5. Observational
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  11. A Review of Emerging Viral Pathogens and Current Concerns for Vertical Transmission of Infection.Medical science monitor : international medical journal of experimental and clinical research · 2024
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shiza VirkDepartment of Internal Medicine, Allegheny Health Network, Pittsburgh, PA 15212, USA.
Karthik GanguDepartment of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Adeel NasrullahDivision of Pulmonology and Critical Care, Allegheny Health Network, Pittsburg, PA 15212, USA.ORCID 0000-0001-7604-6978
Aaisha ShahDepartment of Internal Medicine, Allegheny Health Network, Pittsburgh, PA 15212, USA.
Zohaa FaizDepartment of Medicine, School of Medicine, Aga Khan University, Karachi 74000, Pakistan.ORCID 0000-0002-8362-0875
Umair KhanDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.
David Bradley JacksonDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.ORCID 0000-0001-9413-0313
Anam JavedDepartment of Internal Medicine, Allegheny Health Network, Pittsburgh, PA 15212, USA.
Asif FarooqDepartment of Family and Community Medicine, Texas Tech Health Sciences Center, Lubbock, TX 79409, USA.
Briana DiSilvioDivision of Pulmonology and Critical Care, Allegheny Health Network, Pittsburg, PA 15212, USA.
Tariq CheemaDivision of Pulmonology and Critical Care, Allegheny Health Network, Pittsburg, PA 15212, USA.
Abu Baker SheikhDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM 87106, USA.ORCID 0000-0003-0503-6961

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrent knowledge regarding the association between trimester-specific changes during pregnancy and COVID-19 infection is limited. We utilized the National Inpatient Sample (NIS) database to investigate trimester-specific outcomes among hospitalized pregnant women diagnosed with COVID-19.

resultsOut of 3,447,771 pregnant women identified, those with COVID-19 exhibited higher in-hospital mortality rates in their third trimester compared with those without the virus. Notably, rates of mechanical ventilation, acute kidney injury, renal replacement therapy, and perinatal complications (preeclampsia, HELLP syndrome, and preterm birth) were significantly elevated across all trimesters for COVID-19 patients. COVID-19 was found to be more prevalent among low-income, Hispanic pregnant women.

conclusionsOur findings suggest that COVID-19 during pregnancy is associated with increased risk of maternal mortality and complications, particularly in the third trimester. Furthermore, we observed significant racial and socioeconomic disparities in both COVID-19 prevalence and pregnancy outcomes. These findings emphasize the need for equitable healthcare strategies to improve care for diverse and socioeconomically marginalized groups, ultimately aiming to reduce adverse COVID-19-associated maternal and fetal outcomes.

Indexed as

complicationsCOVID-19HELLPmortalityNational Inpatient Samplepreeclampsiapregnancypreterm birthracial disparitiestrimester-specific outcomes

Identifiers

PMID38001887
PMCPMC10669814

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.