Evidence map›Paper›PMID 38001833›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Demethylcalabaxanthone from

Simona De Vita, Milena Masullo, Sabrina Grambone, Paloma Bermejo Bescós, Sonia Piacente, Giuseppe Bifulco

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. TopicalClinical, cosmetic and investigational dermatology · 2026
    Article
  3. Review
  4. Analysis of Antioxidant Compounds inMolecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Simona De VitaDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, 84084 Fisciano, Italy.ORCID 0000-0002-8203-3580
Milena MasulloDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, 84084 Fisciano, Italy.
Sabrina GramboneDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, 84084 Fisciano, Italy.
Paloma Bermejo BescósDepartamento de Farmacología, Farmacognosia y Botánica, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Sonia PiacenteDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, 84084 Fisciano, Italy.ORCID 0000-0002-4998-2311
Giuseppe BifulcoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, 84084 Fisciano, Italy.
University of Salerno · ITUniversidad Complutense de Madrid · ES

Funding

MIUR Italy 2017A95NCJ
6 · The paper itself

Abstract

Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway activation promotes the expression of antioxidant enzymes in response to rising oxidative stress, resulting in reactive oxygen species (ROS) detoxification and playing a central role in the maintenance of intracellular redox homeostasis and regulation of inflammation. Moreover, the biological effects of Nrf2 pathway activation contribute to reducing apoptosis and enhancing cell survival. The activity of Nrf2 is negatively regulated by Kelch-like ECH-associated protein 1 (Keap1). Prompted by the recent results reporting the impact of xanthone metabolites on oxidative stress, cancer, and inflammation, the antioxidant properties of xanthones isolated from

Indexed as

antioxidant activityGarcinia mangostanamolecular dockingXanthones

Identifiers

PMID38001833
PMCPMC10669650
OpenAlexW4388465059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.