Evidence map›Paper›PMID 38001804›Full record

ArticleAntioxidants (Basel, Switzerland)2023

New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines.

Mohamed A A Orabi, Esam A Orabi, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Basel A Abdel-Wahab, Hiroshi Sakagami, Tsutomu Hatano

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Anti-Neuroinflammatory Effects of Compounds Isolated fromMolecules (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Mohamed A A OrabiDepartment of Pharmacognosy, College of Pharmacy, Najran University, Najran 66454, Saudi Arabia.ORCID 0000-0002-4288-6829
Esam A OrabiDepartment of Chemistry and Biochemistry, Concordia University, 7141 Sherbrooke Street West, Montréal, QC H4B 1R6, Canada.
Ahmed Abdullah Al AwadhDepartment of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran 66454, Saudi Arabia.ORCID 0000-0001-5860-530X
Mohammed Merae AlshahraniDepartment of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran 66454, Saudi Arabia.ORCID 0000-0002-9387-5492
Basel A Abdel-WahabDepartment of Pharmacology, College of Pharmacy, Najran University, Najran 64462, Saudi Arabia.ORCID 0000-0002-5545-6422
Hiroshi SakagamiMeikai University Research Institute of Odontology (M-RIO), 1-1 Keyakidai, Saitama 350-0283, Japan.ORCID 0000-0001-8001-2121
Tsutomu HatanoGraduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Tsushima, Okayama 700-8530, Japan.ORCID 0000-0002-5593-8827
Najran University · SAConcordia University · CAMeikai University · JPOkayama University · JP

Funding

Deanship of Scientific Research at Najran University Distinguished Research Program (grant code NU/DRP/MRC/12/3).
6 · The paper itself

Abstract

Polyphenols have a variety of phenolic hydroxyl and carbonyl functionalities that enable them to scavenge many oxidants, thereby preserving the human redox balance and preventing a number of oxidative stress-related chronic degenerative diseases. In our ongoing investigation of polyphenol-rich plants in search of novel molecules, we resumed the investigation of

Indexed as

antioxidantscytotoxicityhennaLawsonia inermislythraceaemegastigmanemolecular dockingoral cancerpolyphenols

Identifiers

PMID38001804
PMCPMC10669829
OpenAlexW4388126779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.