Evidence map›Paper›PMID 38001735›Full record

ArticleCancers2023

Higher Content but No Specific Activity in Gelatinase B (MMP-9) Compared with Gelatinase A (MMP-2) in Human Renal Carcinoma.

Grzegorz Młynarczyk, Monika Gudowska-Sawczuk, Barbara Mroczko, Marta Bruczko-Goralewska, Lech Romanowicz, Anna Tokarzewicz

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Grzegorz MłynarczykDepartment of Urology, Medical University of Białystok, 15-089 Białystok, Poland.ORCID 0000-0002-1453-8501
Monika Gudowska-SawczukDepartment of Biochemical Diagnostics, Medical University of Białystok, 15-269 Białystok, Poland.ORCID 0000-0003-4854-7155
Barbara MroczkoDepartment of Biochemical Diagnostics, Medical University of Białystok, 15-269 Białystok, Poland.ORCID 0000-0002-4075-8479
Marta Bruczko-GoralewskaDepartment of Medical Biochemistry, Medical University of Białystok, 15-089 Białystok, Poland.
Lech RomanowiczDepartment of Medical Biochemistry, Medical University of Białystok, 15-089 Białystok, Poland.
Anna TokarzewiczDepartment of Medical Biochemistry, Medical University of Białystok, 15-089 Białystok, Poland.ORCID 0000-0001-9951-2433
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gelatinases belong to a group of enzymes known as matrix metalloproteinases (MMPs). Gelatinases A and B (MMP-2 and MMP-9, respectively) are the enzymes with the highest ability to destroy collagen, primarily type IV collagen, which is an essential component of the base membrane. Hence, it can be assumed that they are involved, among other things, with the metastasis process of cancer. As a result, the objective of this study was to assess the presence, activity, and expression of selected gelatinases in human renal cancer. Healthy (

Indexed as

biomarkercancergelatinaseMMP-2MMP-9renal carcinoma

Identifiers

PMID38001735
PMCPMC10670015
OpenAlexW4388830891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.