Evidence map›Paper›PMID 38001694›Full record

ReviewCancers2023

The Potential Preventive and Therapeutic Roles of NSAIDs in Prostate Cancer.

Hossein Maghsoudi, Farhad Sheikhnia, Przemysław Sitarek, Nooshin Hajmalek, Sepideh Hassani, Vahid Rashidi, Sadaf Khodagholi, Seyed Mostafa Mir, Faezeh Malekinejad, Fatemeh Kheradmand and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Hossein MaghsoudiStudent Research Committee, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.ORCID 0000-0002-7549-8793
Farhad SheikhniaStudent Research Committee, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.ORCID 0000-0002-3992-0088
Przemysław SitarekDepartment of Medical Biology, Medical University of Lodz, 90-151 Lodz, Poland.ORCID 0000-0001-5495-3550
Nooshin HajmalekDepartment of Clinical Biochemistry, School of Medicine, Babol University of Medical Sciences, Babol 47176-47754, Iran.
Sepideh HassaniDepartment of Clinical Biochemistry, School of Medicine, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.ORCID 0009-0000-9291-881X
Vahid RashidiStudent Research Committee, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.
Sadaf KhodagholiSchool of Kinesiology and Health Science, York University, Toronto, ON M3J 1P3, Canada.
Seyed Mostafa MirMetabolic Disorders Research Center, Department of Biochemistry and Biophysics, Gorgan Faculty of Medicine, Golestan University of Medical Sciences, Gorgan 49189-36316, Iran.
Faezeh MalekinejadStudent Research Committee, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.
Fatemeh KheradmandDepartment of Clinical Biochemistry, School of Medicine, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.
Mansour GhorbanpourDepartment of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-88349, Iran.ORCID 0000-0002-4790-2701
Navid GhasemzadehDepartment of Clinical Biochemistry, School of Medicine, Urmia University of Medical Sciences, Urmia 57147-83734, Iran.
Tomasz KowalczykDepartment of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-4559-5015
Urmia University · IRArak University · IRBabol University of Medical Sciences · IRGolestan University · IRMedical University of Lodz · PLUniversity of Łódź · PLYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PC) is the second most common type of cancer and the leading cause of death among men worldwide. Preventing the progression of cancer after treatments such as radical prostatectomy, radiation therapy, and hormone therapy is a major concern faced by prostate cancer patients. Inflammation, which can be caused by various factors such as infections, the microbiome, obesity and a high-fat diet, is considered to be the main cause of PC. Inflammatory cells are believed to play a crucial role in tumor progression. Therefore, nonsteroidal anti-inflammatory drugs along with their effects on the treatment of inflammation-related diseases, can prevent cancer and its progression by suppressing various inflammatory pathways. Recent evidence shows that nonsteroidal anti-inflammatory drugs are effective in the prevention and treatment of prostate cancer. In this review, we discuss the different pathways through which these drugs exert their potential preventive and therapeutic effects on prostate cancer.

Indexed as

inflammationnonsteroidal anti-inflammatory drugsNSAIDprostate cancer

Identifiers

PMID38001694
PMCPMC10670652
OpenAlexW4388724802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.